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Details for Product No. ABIN374654

DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6) (C-Term) antibody

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Antigen
Synonyms HLR2, P54, RCK, RGD1564560, 1110001P04Rik, E230023J21Rik, mRCK/P54, p54, rck, p54h, si:ch211-147p17.1, P54H, Xp54, hlr2, me31b
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
Host
Clonality Polyclonal
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN374654
Quantity 0.1 mg
Price
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Peptide with sequence C-AEYHSEPVEDEKP, from the C Terminus of the protein sequence
Specificity This antibody reacts to DDX6. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse, Rat, Canine.
Purification Affinity chromatography
Alternative Name DDX6
Background DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis and cellular growth and division. In the process of mRNA degradation, DDX6 may play a role in mRNA decapping. It forms a complex with DCP1A, DCP2, EDC3 and EDC4/HEDLS.
Alternate names: ATP-dependent RNA helicase DDX6, ATP-dependent RNA helicase p54, DDX-6, DEAD box protein 6, HLR2, Oncogene RCK, RCK
Gene ID 1656
NCBI Accession NP_004388.2
UniProt P26196
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Application Notes Peptide ELISA: 1/16000. Western Blot: 0.1 - 0.3 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Tris buffered saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Cougot, Babajko, Séraphin: "Cytoplasmic foci are sites of mRNA decay in human cells." in: The Journal of cell biology, Vol. 165, Issue 1, pp. 31-40, 2004 (PubMed).

Alternatives for antigen "DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6)", type "Antibodies"
Hosts (25), (5), (3)
Reactivities (30), (5), (4), (2), (1), (1), (1)
Applications (32), (10), (6), (6), (5), (1), (1), (1)
Epitopes (8), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
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