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MYO9B antibody (Myosin IXB) (Internal Region)

Details for Product anti-MYO9B Antibody No. ABIN374691, Supplier: Log in to see
Antigen
  • MYO9B
  • fb53f01
  • wu:fb53f01
  • wu:fc47c07
  • si:dkeyp-66d1.8
  • CELIAC4
  • MYR5
  • myosin IXB
  • myosin IXb
  • myosin-IXb-like
  • MYO9B
  • myo9b
  • Myo9b
  • LOC100364284
Epitope
Internal Region
9
5
1
1
Reactivity
Human
28
10
9
1
1
1
1
1
Host
Goat
16
11
1
Clonality
Polyclonal
Conjugate
This MYO9B antibody is un-conjugated
1
1
1
1
1
1
Application
Western Blotting (WB)
23
22
1
1
1
1
1
Options
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Immunogen Peptide with sequence C-KNDFEPVKQSKAQ, from the internal region of the protein sequence
Specificity This antibody reacts to Myosin IXB.
Purification Affinity chromatography
Alternative Name Myo9b (MYO9B Antibody Abstract)
Background Myosin IX belongs to the family of unconventional myosins, distinct from the classical myosins I and myosins II. Myosin IX, thought to be involved in signal transduction and leukocyte differentiation, includes several isoforms. The rat isoforms are myosin IX/Myr5 (230 kDa) and Myr7 (300 kDa), and the human isoforms are myosin IXa (MYO9A) and myosin IXb (MYO9B). The isoforms of myosin IX have similar overall domain structure and are expressed in many tissues and cell types, although they have distinct tissue expression patterns. The subcellular localization of class IX myosins appears to be partly cytoplasmic, and partly associated with membranes and the actin cytoskeleton. The expression level of myosins IX may vary during development and differentiation.Synonyms: Myosin-IXb, Myr5
Gene ID 4650
NCBI Accession NP_004136
UniProt Q13459
Application Notes Peptide ELISA: 1/2000. Western Blot: 2 - 6 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-MYO9B antibody (Myosin IXB) (Internal Region) (ABIN374691) anti-Myosin IXB (MYO9B) (Internal Region) antibody
Background publications Monsuur, de Bakker, Alizadeh, Zhernakova, Bevova, Strengman, Franke, vant Slot, van Belzen, Lavrijsen, Diosdado, Daly, Mulder, Mearin, Meijer, Meijer, van Oort, Wapenaar, Koeleman, Wijmenga: "Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect." in: Nature genetics, Vol. 37, Issue 12, pp. 1341-4, 2005 (PubMed).