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Ezrin antibody (Internal Region)

EZR Reactivity: Human, Dog WB, IHC (p), EIA Host: Goat Polyclonal unconjugated
Catalog No. ABIN374707
  • Target See all Ezrin (EZR) Antibodies
    Ezrin (EZR)
    Binding Specificity
    • 29
    • 16
    • 12
    • 11
    • 9
    • 9
    • 9
    • 8
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 154
    • 81
    • 74
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Dog
    Host
    • 142
    • 11
    • 3
    • 2
    Goat
    Clonality
    • 138
    • 19
    Polyclonal
    Conjugate
    • 90
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This Ezrin antibody is un-conjugated
    Application
    • 118
    • 54
    • 26
    • 17
    • 16
    • 13
    • 13
    • 13
    • 10
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Sequence
    C-QDYEEKTKKA ER
    Specificity
    This antibody reacts to Ezrin / villin 2.
    Cross-Reactivity (Details)
    Species reactivity (expected):Canine.
    Species reactivity (tested):Human.
    Purification
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    Immunogen
    Peptide with sequence from the internal region of the protein sequence according to NP_003370.2. Genename: VIL2
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    Discover our top product EZR Primary Antibody
  • Application Notes
    ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Ezrin (EZR)
    Alternative Name
    Ezrin (EZR Products)
    Synonyms
    CVIL antibody, CVL antibody, VIL2 antibody, ezr antibody, vil2 antibody, wu:fc05c03 antibody, wu:fj31d06 antibody, cvil antibody, cvl antibody, Vil2 antibody, AW146364 antibody, R75297 antibody, p81 antibody, ezr.S antibody, ezrin antibody, ezrin b antibody, ezrin L homeolog antibody, EZR antibody, ezrb antibody, ezr antibody, Ezr antibody, ezr.L antibody
    Background
    Ezrin (also known as p81, 80K, or cytovillin) is a cytoplasmic protein which is enriched in microvilli and other cell surface structures. Its NH2-terminal domain is associated with the plasma membrane and the COOH-terminal domain with the cytoskeleton. Ezrin has an actin-binding capability. Ezrin is expressed in epithelial cells but not in mesenchymal cells. Ezrin is also expressed by certain epithelial tumors, such as renal cell adenocarcinomas. Ezrin serves as a tyrosine kinase substrate, and is phosphorylated in EGF-stimulated cells.Synonyms: Cytovillin, EZR, VIL2, Villin-2, p81
    Gene ID
    7430, 9606
    UniProt
    P15311
    Pathways
    Maintenance of Protein Location
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