WT1 antibody (N-Term)

Catalog No. ABIN374714

Product Details anti-WT1 Antibody

Target: WT1 (Wilms Tumor 1 (WT1))

Binding Specificity: N-Term

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This WT1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody reacts to Wilms tumor 1. This antibody is expected to recognise all four reported isoforms.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence QDPASTCVPEPASQH, from the N Terminus of the protein sequence

Application Details

Application Notes: ELISA: 1/4000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3, 0.02 % sodium azide, 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for WT1

Target: WT1 (Wilms Tumor 1 (WT1))

Alternative Name: WT1 / Wilms Tumor Protein (WT1 Products)

Synonyms: AWT1 antibody, EWS-WT1 antibody, GUD antibody, NPHS4 antibody, WAGR antibody, WIT-2 antibody, WT33 antibody, CWT1 antibody, WT1 antibody, XWT1a antibody, wt-1 antibody, wt1 antibody, xWT1 antibody, WT-1 antibody, gud antibody, wagr antibody, wt33 antibody, xwt1 antibody, wit-2 antibody, si:ch211-160j6.3 antibody, zgc:152697 antibody, D630046I19Rik antibody, Wt-1 antibody, XWT1b antibody, XeWT1 antibody, Wilms tumor 1 antibody, Wilms tumor 1 S homeolog antibody, wilms tumor 1b antibody, Wilms tumor protein antibody, Wilms tumor 1 homolog antibody, Wilms tumor 1 L homeolog antibody, WT1 antibody, wt1.S antibody, wt1 antibody, wt1b antibody, Wt1 antibody, wt1.L antibody

Background: WT1 encodes multiple isoforms of a zinc finger transcription factor essential for correct mammalian urogenital development. Different WT1 isoforms are thought to regulate transcription and participate in mRNA processing, functions reflected by a complex sub nuclear distribution. In humans, the preservation of the correct isoform ratio and their localization has been reported to be vital, and its disruption to result in disease. This gene has been reported as a useful marker for several types of illnesses. Mutations in this gene lead to the development of Wilm's Tumor, a sporadic and familial childhood kidney tumor.Synonyms: WT33

Gene ID: 7490, 9606

UniProt: P19544

Pathways: Tube Formation