DSCAM antibody (Internal Region)

Catalog No. ABIN374721

Product Details anti-DSCAM Antibody

Target: DSCAM (Down Syndrome Cell Adhesion Molecule (DSCAM))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This DSCAM antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody reacts to DSCAM.

Cross-Reactivity (Details): Species reactivity (expected):Human, Rat, Canine.
Species reactivity (tested):Mouse.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-DSWDSAQRTKDVSPQ, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/4000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for DSCAM

Target: DSCAM (Down Syndrome Cell Adhesion Molecule (DSCAM))

Alternative Name: DSCAM (DSCAM Products)

Synonyms: CHD2-42 antibody, CHD2-52 antibody, Dscam antibody, DSCAM antibody, chd2-42 antibody, chd2-52 antibody, dscam antibody, GB15141 antibody, 4932410A21Rik antibody, 43Bc antibody, CG17800 antibody, CT39257 antibody, DScam antibody, DmDscam antibody, Dm_2R:13612 antibody, Dmel\\CG17800 antibody, Dscam-hv antibody, Dscam1 antibody, FBgn0033159 antibody, Neu1 antibody, dScam antibody, l(2)05518 antibody, l(2)43Bc antibody, p270 antibody, DS cell adhesion molecule antibody, Down syndrome cell adhesion molecule antibody, Down syndrome cell adhesion molecule a antibody, Down syndrome cell adhesion molecule 1 antibody, Down syndrome cell adhesion molecule-like protein Dscam2 antibody, down syndrome cell adhesion molecule antibody, Down syndrome cell adhesion molecule L homeolog antibody, DSCAM antibody, Dscam antibody, dscam antibody, dscama antibody, Dscam1 antibody, LOC5573626 antibody, CpipJ_CPIJ006173 antibody, dscam.L antibody

Background: The Dscam gene encodes a large family of axon guidance receptors and immune receptors via alternative splicing, generating over 38000 isoforms. The gene has been shown to be required for axon guidance, specifically targeting individual neurons to their targets. The gene has also been shown to be involved in the immune system of the fly, different isoforms interact with different pathogens to elicit an immune response. Dscam is a cell adhesion molecule that can mediate cation-independent homophilic binding activity.Synonyms: CHD2, Down syndrome cell adhesion molecule

Gene ID: 1826

NCBI Accession: NP_001380

UniProt: O60469

Pathways: Regulation of Cell Size