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Zinc Metalloproteinase, Ste24 (Zmpste24) (C-Term) antibody

Details for Product No. ABIN374738, Supplier: Log in to see
Antigen
  • DDBDRAFT_0189115
  • DDBDRAFT_0237846
  • DDB_0189115
  • DDB_0237846
  • F2N1.21
  • F2N1_21
  • STE24
  • FACE-1
  • FACE1
  • HGPS
  • PRO1
  • Ste24p
  • A530043O15Rik
  • D030046F19
  • Face-1
  • MADB
  • fi45a02
  • wu:fi45a02
  • zgc:55655
  • zinc metallopeptidase (STE24 homolog, S. cerevisiae)
  • zinc metallopeptidase STE24
  • zinc metallopeptidase STE24 homolog (S. cerevisiae)
  • CAAX prenyl protease
  • peptidase family M48 family protein
  • zinc metallopeptidase, STE24
  • zinc metallopeptidase, STE24 homolog
  • ZMPSTE24
  • zmpste24
  • ATSTE24
  • Zmpste24
Epitope
C-Term
54
19
14
14
14
12
8
3
2
2
2
1
1
1
Reactivity
Human
109
32
12
10
2
2
2
1
1
1
Host
Goat
95
15
Clonality
Polyclonal
Conjugate
Un-conjugated
11
7
7
7
7
7
3
3
3
2
2
2
2
2
Application
Western Blotting (WB)
105
57
27
13
13
7
2
1
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Immunogen Peptide with sequence C-ERLQALKTMKQH, from the C Terminus of the protein sequence
Specificity This antibody reacts to FACE1.
Purification Affinity chromatography
Alternative Name ZMPSTE24 (Zmpste24 Antibody Abstract)
Background The protein encoded by this gene is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It proteolytically removes the C-terminal three residues of farnesylated proteins, and acts on lamin A/C.Synonyms: CAAX prenyl protease 1 homolog, FACE-1, FACE1, Farnesylated proteins-converting enzyme 1, Prenyl protein-specific endoprotease 1, STE24, Zinc metalloproteinase Ste24 homolog
Gene ID 10269, 9606
UniProt O75844
Research Area Proteolysis / Ubiquitin, Cytoskeleton
Application Notes Peptide ELISA: 1/128000. Western Blot: 0.5 - 1.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-Zinc Metalloproteinase, Ste24 (Zmpste24) (C-Term) antibody (ABIN374738) anti-Zinc Metalloproteinase, Ste24 (Zmpste24) (C-Term) antibody
Background publications Fong, Frost, Meta, Qiao, Yang, Coffinier, Young: "A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria." in: Science (New York, N.Y.), Vol. 311, Issue 5767, pp. 1621-3, 2006 (PubMed).