DPP4 antibody (Internal Region)

Catalog No. ABIN374762

Product Details anti-DPP4 Antibody

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This DPP4 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-PPHFDKSKKY P

Specificity: This antibody recognizes CD26 / DPP4.

Cross-Reactivity (Details): Species reactivity (expected):Human, Mouse, Canine.
Species reactivity (tested):Rat.

Purification: Affinity Chromatography

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_001926.2 Genename: DPP4

Application Details

Application Notes: Peptide ELISA: 1/64000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-DPP4 antibody (ABIN374762)

Antel, Freedman, Brodovsky, Francis, Duquette: "Activated suppressor cell function in severely disabled patients with multiple sclerosis." in: Annals of neurology, Vol. 25, Issue 2, pp. 204-7, (1989) (PubMed).

Target Details for DPP4

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Alternative Name: CD26 / DPP4 (DPP4 Products)

Synonyms: ADABP antibody, ADCP2 antibody, CD26 antibody, DPPIV antibody, TP103 antibody, MGC81966 antibody, MOP9.8 antibody, MOP9_8 antibody, DPP4 antibody, si:ch73-2d23.3 antibody, Cd26 antibody, Dpp-4 antibody, THAM antibody, dipeptidyl peptidase 4 antibody, dipeptidyl-peptidase 4 S homeolog antibody, prolyl oligopeptidase family protein antibody, dipeptidyl-peptidase 4 antibody, dipeptidylpeptidase 4 antibody, DPP4 antibody, dpp4.S antibody, AT5G24260 antibody, dpp4 antibody, Dpp4 antibody

Background: CD26 [also known as dipeptidyl peptidase IV (DPP IV), adenosine deaminase (ADA) binding protein] is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection.Synonyms: ADABP, ADCP2, Adenosine deaminase complexing protein 2, DPP IV, Dipeptidyl peptidase 4, Dipeptidyl peptidase IV, T-cell activation antigen CD26, TP103

Gene ID: 1803, 9606

UniProt: P27487

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity