COL7 antibody (Internal Region)

Catalog No. ABIN374776

Product Details anti-COL7 Antibody

Target: COL7 (Collagen, Type VII (COL7))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This COL7 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody reacts to Collagen, type VII. This product does not work on cryostat sections of Normal Human Skin.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Human, Canine, Porcine.
Species reactivity (tested):Rat.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-TVQYSDDPRTEF, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/32000. Western Blot: 0.1 - 1.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for COL7

Target: COL7 (Collagen, Type VII (COL7))

Alternative Name: Collagen Type VII (COL7 Products)

Synonyms: COL7A1 antibody, collagen type VII alpha 1 chain antibody, collagen, type VII, alpha 1 antibody, COL7A1 antibody, col7a1 antibody

Background: Type VII collagen fibrils are composed of three identical alpha collagen chains. It's location is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in the collagen V11 gene are associated with all forms of dystrophic epidermolysis bullosa.Synonyms: COL7A1, LC collagen, Long-chain collagen

Gene ID: 1294

NCBI Accession: NP_000085

UniProt: Q02388