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Details for Product No. ABIN374790

Glucose-6-Phosphate Dehydrogenase (G6PD) (Internal Region), (AA 308-320) antibody

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Antigen
Synonyms G6PD1, G6pdx, g6pd, G6PD, G6pd, Dsim\\\\G6pd, Dsim\\\\G6pdh, G-6PD, dsim_GLEANR_8868, Dsim\\\\GD24877, GD24877, Zw, g6pdh, g6pd2, fj78b06, wu:fj78b06, si:dkey-90a13.8, BA3433, PSPTO1300, PSPTO3121
Epitope
»Alternatives Internal Region, AA 308-320
Reactivity
»Alternatives Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN374790
Quantity 0.1 mg
Price
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Synthetic Peptide from the internal region (aa 308-320) of Human G6PD. Genename: G6PD
Sequence C-STNSDDVRDEKVK
Specificity This antibody is expected to recognise both reported isoforms (NP_000393.4 and NP_001035810.1).
Purification Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography.
Alternative Name G6PD
Background Glucose 6 Phosphate Dehydrogenase (G6PD) produces pentose sugars for nucleic acid synthesis and is the main producer of NADPH reducing power. Catalytic activity: D glucose 6 phosphate + NADP(+) = D glucono 1,5 lactone 6 phosphate + NADPH. Defects in G6PD are the cause of chronic non spherocytic haemolytic anemia (CNSHA). G6PD deficiency is the most common human enzyme deficiency, one benefit of having G6PD deficiency is that it confers a resistance to malaria.
Alternate names: Glucose-6-P-Dehydrogenase, Glucose-6-phosphate 1-dehydrogenase
Gene ID 2539
NCBI Accession 9606
UniProt P11413
Application Notes Peptide ELISA: Limit dilution: 1/32000. Western Blot: Use at 0.03-0.1 µg/ml. Detects a double band of ~55-60 kDa band in HumanTestis, Thyroid and Tonsil lysates. Immunohistochemistry: 2-4 µg/ml. In paraffin embedded Human Testis shows strongcytoplasm staining in spermatogonia. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Tris buffered saline, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% Sodium Azide as preservative.
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Guindo, Fairhurst, Doumbo et al.: "X-linked G6PD deficiency protects hemizygous males but not heterozygous females against severe malaria." in: PLoS medicine, Vol. 4, Issue 3, pp. e66, 2007 (PubMed).

Alternatives for antigen "Glucose-6-Phosphate Dehydrogenase (G6PD)", type "Antibodies"
Hosts (93), (37), (24)
Reactivities (102), (47), (43), (28), (26), (24), (12), (12), (9), (6), (3), (1), (1)
Applications (122), (95), (30), (28), (23), (20), (16), (14), (11), (11), (7), (5), (5), (4), (2), (1), (1)
Conjugates (22), (8), (4), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Epitopes (9), (6), (5), (4), (4), (3), (2), (1), (1), (1), (1), (1), (1)
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