anti-FOXO4 antibody (Forkhead Box O4) (Internal Region)

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Antigen
Synonyms FOXO4, foxo4, AFX, AFX1, MLLT7, Afxh, Mllt7, afx, RGD1561201
Alternatives
Epitope
Internal Region
(41), (37), (25), (22), (18), (11), (9), (7), (5), (5), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(262), (153), (101), (7), (5), (2), (2), (1), (1), (1), (1)
Host
Goat
(241), (15), (7)
Clonality
Polyclonal
Conjugate
This FOXO4 antibody is un-conjugated
(6), (6), (6), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1)
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(202), (102), (85), (38), (35), (34), (22), (6), (5), (1), (1)
Pubmed 1 reference available
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Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Peptide with sequence C-EAASQDRMPQDLD, from the internal region of the protein sequence
Specificity This antibody recognizes FOXO4 / MLLT7.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity Chromatography
Alternative Name FOXO4 / AFX1 / MLLT7 (FOXO4 Antibody Abstract)
Background FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.Synonyms: Fork head domain transcription factor AFX1, Forkhead box protein O4
Molecular Weight 53.7 kDa (NP_005929.2).
Gene ID 4303, 9606
UniProt P98177
Pathways Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes Peptide ELISA: 1/64000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Image no. 1 for anti-FOXO4 antibody (Forkhead Box O4) (Internal Region) (ABIN374816) anti-Forkhead Box O4 (FOXO4) (Internal Region) antibody
Image no. 2 for anti-FOXO4 antibody (Forkhead Box O4) (Internal Region) (ABIN374816) anti-Forkhead Box O4 (FOXO4) (Internal Region) antibody (Image 2)
Background publications Paik, Kollipara, Chu et al.: "FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis." in: Cell, Vol. 128, Issue 2, pp. 309-23, 2007 (PubMed).

Catalog No. ABIN374816
$379.50
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