Forkhead Box O4 (FOXO4) (Internal Region) antibody

Details for Product No. ABIN374816
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Antigen
Synonyms AFX, AFX1, MLLT7, Afxh, Mllt7, afx, RGD1561201, FOXO4, foxo4
Epitope
Internal Region
(39), (21), (20), (17), (17), (6), (5), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(191), (147), (110), (61), (48), (48), (36), (3)
Host
Goat
(188), (4), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5)
Application
ELISA, Western Blotting (WB)
(141), (74), (50), (42), (39), (25), (22), (2)
Pubmed 1 reference available
Catalog no. ABIN374816
Quantity 0.1 mg
Price
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Immunogen Peptide with sequence C-EAASQDRMPQDLD, from the internal region of the protein sequence
Specificity This antibody recognizes FOXO4 / MLLT7. Species Reactivity: Tested: Human.
Purification Affinity Chromatography
Alternative Name FOXO4 / AFX1 / MLLT7
Background FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.
Alternate names: Fork head domain transcription factor AFX1, Forkhead box protein O4
Gene ID 4303
NCBI Accession 9606
UniProt P98177
Application Notes Peptide ELISA: 1/64000. Western Blot: 1 - 3 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Tris buffered saline, pH~7.3 0.02% Sodium Azide 0.5% BSA
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Supplier Images
anti-Forkhead Box O4 (FOXO4) (Internal Region) antibody anti-Forkhead Box O4 (FOXO4) (Internal Region) antibody
anti-Forkhead Box O4 (FOXO4) (Internal Region) antibody (2) anti-Forkhead Box O4 (FOXO4) (Internal Region) antibody (Image 2)
Background publications Paik, Kollipara, Chu et al.: "FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis." in: Cell, Vol. 128, Issue 2, pp. 309-23, 2007 (PubMed).

Hosts (188), (4), (2)
Reactivities (191), (147), (110), (61), (48), (48), (36), (3)
Applications (141), (74), (50), (42), (39), (25), (22), (2)
Conjugates (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5)
Epitopes (39), (21), (20), (17), (17), (6), (5), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1)
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