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NPY2R antibody (Internal Region)

NPY2R Reactivity: Mouse, Rat WB, IP, EIA Host: Goat Polyclonal unconjugated
Catalog No. ABIN374839
  • Target See all NPY2R Antibodies
    NPY2R (Neuropeptide Y Receptor Y2 (NPY2R))
    Binding Specificity
    • 15
    • 14
    • 13
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 51
    • 27
    • 21
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 53
    • 2
    Goat
    Clonality
    • 55
    Polyclonal
    Conjugate
    • 27
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NPY2R antibody is un-conjugated
    Application
    • 48
    • 30
    • 13
    • 13
    • 10
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes Neuropeptide Y receptor 2.
    Cross-Reactivity (Details)
    Species reactivity (expected):Canine (Dog).
    Species reactivity (tested):Human, Mouse, Rat.
    Purification
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    Immunogen
    Peptide with sequence C-KAKKNLEVKKNN, from the internal region of the protein sequence Genename: Npy2r .Remarks: This antibody was designed using the Mouse sequence, which differs by 1 amino acid from the Human sequence.
    Top Product
    Discover our top product NPY2R Primary Antibody
  • Application Notes
    Peptide ELISA: Detection Limit: 1/32000. Western Blot: 0.1-0.3 μg/mL. Approx 40+45 kDa bands observed in Mouse Brain and RatBrain lysates (calculated MW of 42.5 kDa according to NP032757.1). A customer successfully used this product for immunoprecipitation of Human Y2R.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    NPY2R (Neuropeptide Y Receptor Y2 (NPY2R))
    Alternative Name
    Neuropeptide Y Receptor 2 (NPY2R Products)
    Synonyms
    NPY2-R antibody, npy2r antibody, si:dkey-30k22.9 antibody, NPY-Y2 antibody, neuropeptide Y receptor Y2 antibody, NPY2R antibody, npy2r antibody, Npy2r antibody
    Background
    Neuropeptide Y (NPY) receptors are members of a G protein coupled receptor superfamily and they mediate a variety of physiological responses including feeding and vasoconstriction. The endogenous ligands of NPY receptors are a family of structurally related peptides, including NPY, peptide YY (PYY), and pancreatic polypeptide (PP). Increased activity of NPY and its receptors, Y1R, Y2R, and Y5R has been found in the brain in many forms of experimental obesity. Furthermore, several association studies have supported the association between NPY2R and obesity.Synonyms: NPY-Y2 receptor, NPY2-R, Neuropeptide Y receptor 2, Y2 receptor
    Gene ID
    4887, 9606
    UniProt
    P49146
    Pathways
    cAMP Metabolic Process, Synaptic Membrane, Feeding Behaviour
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