NPFFR1 antibody (Internal Region)

Catalog No. ABIN374925

Product Details anti-NPFFR1 Antibody

Target: NPFFR1 (Neuropeptide FF Receptor 1 (NPFFR1))

Binding Specificity: Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This NPFFR1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody reacts to NPFFR1.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-RPSGSHKEAYSERP, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/64000. Western Blot: 0.03 - 0.1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for NPFFR1

Target: NPFFR1 (Neuropeptide FF Receptor 1 (NPFFR1))

Alternative Name: Neuropeptide FF Receptor 1 (NPFFR1 Products)

Synonyms: GPR147 antibody, NPFF1 antibody, NPFF1R1 antibody, OT7T022 antibody, Gm236 antibody, Gpr147 antibody, RFRPR antibody, MGC83178 antibody, NPFFR1 antibody, LOC100230250 antibody, neuropeptide FF receptor 1 antibody, neuropeptide FF receptor 1 L homeolog antibody, inorganic pyrophosphatase-like antibody, NPFFR1 antibody, Npffr1 antibody, npffr1.L antibody, LOC100230250 antibody

Background: The central nervous system octapeptide, neuropeptide FF (NPFF), is believed to play a role in pain modulation and opiate tolerance. Two G protein-coupled receptors, NPFF1 and NPFF2, have been isolated from human and rat central nervous system tissues. Localization of mRNA and binding sites of these receptors in the dorsal horn of the spinal cord, the lateral hypothalamus, the spinal trigeminal nuclei, and the thalamic nuclei suggest a role for NPFF in pain modulation.Synonyms: G-protein coupled receptor 147, GPR147, NP receptor, NPFF receptor, NPFF1, NPFFR1, RFamide-related peptide receptor OT7T022

Gene ID: 64106, 9606

UniProt: Q9GZQ6

Pathways: cAMP Metabolic Process