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GOT2 antibody (Internal Region)

GOT2 Reactivity: Human, Mouse, Rat WB Host: Goat Polyclonal unconjugated
Catalog No. ABIN374942
  • Target See all GOT2 Antibodies
    GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))
    Binding Specificity
    • 13
    • 8
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 77
    • 38
    • 19
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 70
    • 10
    • 3
    • 2
    Goat
    Clonality
    • 73
    • 10
    Polyclonal
    Conjugate
    • 43
    • 10
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This GOT2 antibody is un-conjugated
    Application
    • 65
    • 40
    • 29
    • 12
    • 11
    • 10
    • 9
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    This antibody reacts to GOT2.
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography
    Immunogen
    Peptide with sequence CKDADEAKRVES, from the internal region of the protein sequence
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    Discover our top product GOT2 Primary Antibody
  • Application Notes
    Peptide ELISA: 1/32000. Western Blot: 0.03 - 0.1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0,5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))
    Alternative Name
    GOT2 (GOT2 Products)
    Synonyms
    KAT4 antibody, KATIV antibody, mitAAT antibody, AI789014 antibody, Got-1 antibody, cAspAT antibody, cCAT antibody, AL022787 antibody, FABP-pm antibody, Got-2 antibody, mAspAT antibody, ASPATA antibody, got2 antibody, zgc:66329 antibody, fj40h07 antibody, wu:fj40h07 antibody, zgc:56425 antibody, glutamic-oxaloacetic transaminase 2 antibody, glutamic-oxaloacetic transaminase 1, soluble antibody, glutamatic-oxaloacetic transaminase 2, mitochondrial antibody, glutamic-oxaloacetic transaminase 2a, mitochondrial antibody, glutamic-oxaloacetic transaminase 2 L homeolog antibody, Aspartate amino transferase activity antibody, glutamic-oxaloacetic transaminase 2b, mitochondrial antibody, GOT2 antibody, got2 antibody, Got1 antibody, Got2 antibody, got2a antibody, got2.L antibody, AST antibody, got2b antibody
    Background
    GOT2 [Glutamate oxaloacetate transaminase] is a ubiquitous pyridoxal phosphate dependent enzyme which exists in both mitochondrial and cytosolic forms. The enzyme plays an important role in amino acid metabolism and in the urea and tricarboxylic acid cycles. The 2 isoenzymes are homodimeric. In liver about 80 % of the enzyme activity is mitochondrial in origin, whereas in serum the enzyme activity is largely cytosolic. Although the mitochondrial and soluble forms of GOT are coded by different chromosomes, the 2 show close homology in amino acid sequence and were presumably derived from a common ancestral gene. Serum GOT [with SGPT] levels are usually elevated in states of hepatocellular injury (injury to the liver cells), the highest levels are associated with hepatitis of a viral origin. High levels are also found after myocardial infarction, when SGPT levels are lower.Synonyms: Aspartate aminotransferase, FABP-1, FABPpm, Fatty acid-binding protein, Transaminase A, mAspAT, mitochondrial
    Gene ID
    2806, 9606
    UniProt
    P00505
    Pathways
    Monocarboxylic Acid Catabolic Process
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