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IGFBP6 antibody (Internal Region)

IGFBP6 Reactivity: Human, Cow WB Host: Goat Polyclonal unconjugated
Catalog No. ABIN374965
  • Target See all IGFBP6 Antibodies
    IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))
    Binding Specificity
    • 15
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 35
    • 21
    • 17
    Human, Cow
    Host
    • 41
    • 11
    • 2
    • 1
    Goat
    Clonality
    • 44
    • 11
    Polyclonal
    Conjugate
    • 30
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IGFBP6 antibody is un-conjugated
    Application
    • 37
    • 20
    • 13
    • 13
    • 12
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    This antibody reacts to IGFBP6.
    Cross-Reactivity (Details)
    Species reactivity (expected):Bovine.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography
    Immunogen
    Peptide with sequence C-RPQDVNRRDQQRNP, from the internal region of the protein sequence
    Top Product
    Discover our top product IGFBP6 Primary Antibody
  • Application Notes
    Peptide ELISA: 1/32000. Western Blot: 0.5 - 1.5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0,5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))
    Alternative Name
    IGFBP6 (IGFBP6 Products)
    Synonyms
    IBP6 antibody, IGFBP-6 antibody, IGF-BP6 antibody, RBP6A antibody, IGFBP6 antibody, igfbp6 antibody, insulin like growth factor binding protein 6 antibody, insulin-like growth factor binding protein 6 antibody, IGFBP6 antibody, Igfbp6 antibody, IGFBP-6 antibody, igfbp6 antibody
    Background
    IGFBP6 (IGF binding protein 6) is a member of the IGFBP family that regulates the actions of IGFs. It acts extracellularly in an autocrine/paracrine manner. IGFBP6 binds preferentially to IGF-II. IGFBP6 has been shown to inhibit the growth of tumour cells and to promote apotosis. IGFBP6 has been shown to be imported into the nuclei of rhabdomyosarcoma and HEK-293 cells. This is mediated by a NLS sequence that bears limited homology to those found in IGFBP-3 and -5. Deletion of the NLS segment abolishes the pro-apoptotic effect of IGFBP6.Synonyms: IBP-6, IBP6, IGF-binding protein 6, IGFBP-6, Insulin-like growth factor-binding protein 6
    Gene ID
    3489, 9606
    UniProt
    P24592
    Pathways
    WNT Signaling, Myometrial Relaxation and Contraction
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