C-Type Lectin Domain Family 1, Member B (CLEC1B) (Internal Region) antibody

Catalog No. ABIN374981

Product Details

Target: C-Type Lectin Domain Family 1, Member B (CLEC1B)

Binding Specificity: Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to CLEC2 / CLEC1B.

Purification: Affinity chromatography

Immunogen: Peptide with sequence KGHKCSPCDTNWRY, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/1000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details

Target: C-Type Lectin Domain Family 1, Member B (CLEC1B)

Alternative Name: CLEC1B (CLEC1B Products)

Synonyms: 1810061I13Rik antibody, CLEC2 antibody, CLEC2B antibody, PRO1384 antibody, QDED721 antibody, Clec-2 antibody, Clec2 antibody, CLEC1B antibody, RGD1563517 antibody, CLEC9A antibody, C-type lectin domain family 1 member B antibody, C-type lectin domain family 1, member b antibody, C-type lectin domain family 1, member B antibody, CLEC1B antibody, Clec1b antibody

Target Type: Viral Protein

Background: Natural killer (NK) cells express multiple C-type (calcium-dependent) lectin-like receptors, that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC1B (also known as CLEC-2) is a C-type lectin-like receptor expressed in myeloid cells and NK cells. CLEC1B acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets. It also acts as a receptor for the platelet-aggregating snake venom protein rhodocytin.Synonyms: C-type lectin domain family 1 member B, C-type lectin-like receptor 2, CLEC-2, CLEC2

Gene ID: 51266

NCBI Accession: NP_001092901

UniProt: Q9P126