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ERAP2 antibody (Internal Region)

ERAP2 Reactivity: Human, Cow, Dog WB, EIA Host: Goat Polyclonal unconjugated
Catalog No. ABIN374998
  • Target See all ERAP2 Antibodies
    ERAP2 (Endoplasmic Reticulum Aminopeptidase 2 (ERAP2))
    Binding Specificity
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 20
    • 2
    • 1
    • 1
    Human, Cow, Dog
    Host
    • 15
    • 3
    • 2
    Goat
    Clonality
    • 19
    • 1
    Polyclonal
    Conjugate
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ERAP2 antibody is un-conjugated
    Application
    • 10
    • 9
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to ERAP2.
    Cross-Reactivity (Details)
    Species reactivity (expected):Canine, Bovine.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography
    Immunogen
    Peptide with sequence C-QYLKKFSYRNAKND, from the internal region of the protein sequence
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    Discover our top product ERAP2 Primary Antibody
  • Application Notes
    Peptide ELISA: 1/16000. Western Blot: 0.5 - 1.5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0,5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    ERAP2 (Endoplasmic Reticulum Aminopeptidase 2 (ERAP2))
    Alternative Name
    ERAP2 / LRAP (ERAP2 Products)
    Synonyms
    L-RAP antibody, LRAP antibody, ERAP2 antibody, zgc:172163 antibody, endoplasmic reticulum aminopeptidase 2 antibody, ERAP2 antibody, erap2 antibody
    Background
    ERAP2 is an aminopeptidase that plays a central role in peptide trimming. Major histocompatibility complex (MHC) class I molecules rely on aminopeptidases such as ERAP2 to trim precursors to antigenic peptides in the endoplasmic reticulum (ER) following cleavage in the cytoplasm by tripeptidyl peptidase II. ERAP2 preferentially hydrolyzes the basic residues Arg and Lys.Synonyms: Endoplasmic reticulum aminopeptidase 2, L-RAP, Leukocyte-derived arginine aminopeptidase
    Gene ID
    64167
    NCBI Accession
    NP_001123612
    UniProt
    Q6P179
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