CHRNB3 antibody (Internal Region)

Catalog No. ABIN374999

Product Details anti-CHRNB3 Antibody

Target: CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This CHRNB3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to CHRNB3.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-SRHVKKEHFISQ, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CHRNB3

Target: CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))

Alternative Name: Neuronal Acetylcholine Receptor Subunit beta-3 (CHRNB3 Products)

Synonyms: 5730417K16Rik antibody, Acrb3 antibody, NACHR antibody, CHRNB3 antibody, chrnb3 antibody, cholinergic receptor nicotinic beta 3 subunit antibody, neuronal acetylcholine receptor subunit beta-3 antibody, cholinergic receptor, nicotinic, beta polypeptide 3 antibody, cholinergic receptor, nicotinic beta 3 L homeolog antibody, cholinergic receptor, nicotinic beta 3 antibody, cholinergic receptor, nicotinic, beta 3b (neuronal) antibody, cholinergic receptor, nicotinic, beta polypeptide 3a antibody, CHRNB3 antibody, CpipJ_CPIJ012638 antibody, Chrnb3 antibody, chrnb3.L antibody, chrnb3 antibody, chrnb3b antibody, chrnb3a antibody

Background: The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be (hetero)pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if, like muscle alpha-1, they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits.Synonyms: CHRNB3, Nicotinic acetylcholine receptor subunit beta 3

Gene ID: 1142, 9606

UniProt: Q05901