MEPCE
Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Pig
WB, IP
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Peptide ELISA: 1/16000. Western Blot: 0.3 - 1 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
MEPCE belongs to the methyltransferase superfamily and contains one BIN3 domain. It is an S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it. MEPCE is expressed in chronic myeloid leukemia cells, adrenal gland, brain, cerebellum, kidney, lung, mammary gland and testis. It is weakly or not expressed in other tissues.Synonyms: 7SK snRNA methylphosphate capping enzyme, Bicoid-interacting protein 3 homolog, Bin-3 homolog, Bin3 homolog