DPM1 antibody (N-Term)

Catalog No. ABIN375033

Product Details anti-DPM1 Antibody

Target: DPM1 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 1, Catalytic Subunit (DPM1))

Binding Specificity: N-Term

Reactivity: Mouse, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This DPM1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody reacts to Dpm1.

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Rat.

Purification: Affinity chromatography

Immunogen: Peptide with sequence PQGRSSRQDKYS-C, from the N-Terminus of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/64000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for DPM1

Target: DPM1 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 1, Catalytic Subunit (DPM1))

Alternative Name: DPM1 (DPM1 Products)

Synonyms: DPM1 antibody, zgc:101018 antibody, MGC114892 antibody, AI118379 antibody, AI194292 antibody, CDGIE antibody, MPDS antibody, DPMS antibody, dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit antibody, dolichyl-phosphate mannosyltransferase subunit 1, catalytic antibody, dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit S homeolog antibody, dolichol-phosphate (beta-D) mannosyltransferase 1 antibody, dpm1 antibody, DPM1 antibody, dpm1.S antibody, Dpm1 antibody

Background: Dolichol-phosphate mannose (DPM1) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Defective surface expression of GPI-anchored proteins occurs when there is a lack of DPM1. DPM1 is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2.Synonyms: DPM synthase, DPM-1, Dolichol-phosphate mannose synthase, Dolichol-phosphate mannosyltransferase, Dolichyl-phosphate beta-D-mannosyltransferase, EC=2.4.1.83, MPD synthase, Mannose-P-dolichol synthase

Gene ID: 8813

NCBI Accession: NP_003850

UniProt: O60762

Pathways: Inositol Metabolic Process