LIPG antibody (Internal Region)

Catalog No. ABIN375035

Product Details anti-LIPG Antibody

Target: LIPG (Lipase, Endothelial (LIPG))

Binding Specificity: Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This LIPG antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody reacts to Endothelial lipase.

Purification: Ammonium Sulphate Precipitation, followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-RFNLRTSKDPEHEG, from the internal region of the protein sequence of Human LIPG.

Application Details

Application Notes: Peptide ELISA: Detection limit dilution: 1/16000. Western Blot: 0.3-1 μg/mL. Approx.70 kDa band observed in Human Liver lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for LIPG

Target: LIPG (Lipase, Endothelial (LIPG))

Alternative Name: LIPG (LIPG Products)

Synonyms: zgc:55345 antibody, MGC69106 antibody, LIPG antibody, lipe antibody, EDL antibody, EL antibody, PRO719 antibody, 3110013K01Rik antibody, lipase antibody, mEDL antibody, lipase G, endothelial type antibody, lipase, endothelial antibody, lipase, endothelial L homeolog antibody, endothelial lipase antibody, lipase, hormone-sensitive antibody, LIPG antibody, lipg antibody, lipg.L antibody, CpipJ_CPIJ004802 antibody, lipe antibody, LOC509808 antibody, Lipg antibody

Background: Endothelial lipase (EL or EDL) is a member of the triglyceride lipase gene family, which includes lipoprotein lipase and hepatic lipase. These family members play a crucial role in the metabolism of lipids. Compared to other family members, EL exhibits mainly phospholipase activity and little triglyceride lipase activity. EL is produced mainly by vascular endothelial cells but also by macrophages, smooth muscle cells, and hepatocytes. The overexpression of endothelial lipase has been shown to reduce HDL cholesterol levels and the deficiency of EL appears to elevate HDL cholesterol levels in animals.Synonyms: EC=3.1.1.3, EDL, EL, Endothelial cell-derived lipase, Endothelial lipase, LIPG

Gene ID: 9388

NCBI Accession: NP_006024

UniProt: Q9Y5X9