COL4A3BP antibody (Internal Region)

Catalog No. ABIN375044

Product Details anti-COL4A3BP Antibody

Target: COL4A3BP (Collagen, Type IV, alpha 3 (Goodpasture Antigen) Binding Protein (COL4A3BP))

Binding Specificity: AA 396-411, Internal Region

Reactivity: Human, Cow, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This COL4A3BP antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody reacts to COL4A3BP.

Cross-Reactivity (Details): Species reactivity (expected):Canine, Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-KREDSWQKRLDKETEK, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/2000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-COL4A3BP antibody (ABIN375044)

Kudo, Kumagai, Tomishige, Yamaji, Wakatsuki, Nishijima, Hanada, Kato: "Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 2, pp. 488-93, (2008) (PubMed).

Target Details for COL4A3BP

Target: COL4A3BP (Collagen, Type IV, alpha 3 (Goodpasture Antigen) Binding Protein (COL4A3BP))

Alternative Name: COL4A3BP (COL4A3BP Products)

Synonyms: COL4A3BP antibody, 2810404O15Rik antibody, 9230101K08Rik antibody, AU016711 antibody, CERT antibody, GPBP antibody, col4a3bp antibody, wu:fc37f11 antibody, zgc:92147 antibody, CERTL antibody, STARD11 antibody, cert antibody, certl antibody, cetp antibody, gpbp antibody, stard11 antibody, collagen type IV alpha 3 binding protein antibody, collagen, type IV, alpha 3 (Goodpasture antigen) binding protein antibody, collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a antibody, collagen, type IV, alpha 3 (Goodpasture antigen) binding protein L homeolog antibody, COL4A3BP antibody, Col4a3bp antibody, col4a3bpa antibody, col4a3bp.L antibody

Background: COL4A3BP is a kinase that specifically phosphorylates the N terminal region of the non collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Two transcripts exist for this gene.Synonyms: CERT, Ceramide transfer protein, Collagen type IV alpha-3-binding protein, GPBP, Goodpasture antigen-binding protein, STARD11, START domain-containing protein 11, StAR-related lipid transfer protein 11, StARD11, hCERT

Gene ID: 10087, 9606

UniProt: Q9Y5P4