ITPKC
Reactivity: Human
WB, ELISA, IHC, IF, IP
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Peptide ELISA: 1/2000. Western Blot: 1 - 3 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
0,5 mg/mL
Buffer
Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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Background
Inositol 1,4,5-trisphosphate 3-kinase (ITPK) catalyzes the phosphorylation of Ins(1,4,5)P3 to Ins(1,3,4,5)P4, both of which are modulators of calcium homeostasis. ITPK isoforms include ITPKA (MIM 147521), ITPKB (MIM 147522), and ITPKC (also known as IP3KC), all of which contain a conserved catalytic unit in their C termini, but have unique N-terminal sequences and tissue distributions.Synonyms: 4, 5-trisphosphate 3-kinase C, IP3K-C, IP3KC, Inositol 1, Inositol-trisphosphate 3-kinase C, InsP3-kinase C