PSMG1 antibody (C-Term)

Catalog No. ABIN375103

Product Details anti-PSMG1 Antibody

Target: PSMG1 (Proteasome (Prosome, Macropain) Assembly Chaperone 1 (PSMG1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit

Host: Goat

Clonality: Polyclonal

Conjugate: This PSMG1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: C-KLMTTNEIQS NIYT

Specificity: This antibody reacts to DSCR2 / PSMG1.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Rabbit, Canine and Bovine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography.

Immunogen: Peptide with sequence from the C Terminus of the protein sequence.

Application Details

Application Notes: Peptide ELISA: 1/64000. Western Blot: Use at 0.3-1.0 μg/mL. Approx.30 kDa band observed in lysates in Jurkat (calculated MW of 30.0 kDa according toNP_982257.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris-saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PSMG1

Target: PSMG1 (Proteasome (Prosome, Macropain) Assembly Chaperone 1 (PSMG1))

Alternative Name: PSMG1 (PSMG1 Products)

Synonyms: DSCR2 antibody, dscr2 antibody, zgc:91806 antibody, wu:fl12g04 antibody, wu:fu18c08 antibody, PSMG1 antibody, pac1 antibody, c21lrp antibody, lrpc21 antibody, DDBDRAFT_0206024 antibody, DDBDRAFT_0304546 antibody, DDB_0206024 antibody, DDB_0304546 antibody, C21LRP antibody, LRPC21 antibody, PAC-1 antibody, PAC1 antibody, AW552102 antibody, Dscr2 antibody, proteasome assembly chaperone 1 antibody, proteasome (prosome, macropain) assembly chaperone 1 antibody, proteasome (prosome, macropain) assembly chaperone 1 L homeolog antibody, PSMG1 antibody, psmg1 antibody, psmg1.L antibody, psmG1 antibody, Psmg1 antibody

Background: PSMG1 is a chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. There are two named isoforms.Synonyms: C21-LRP, C21LRP, Chromosome 21 leucine-rich protein, DSCR2, Down syndrome critical region protein 2, PAC-1, PAC1, PSMG-1, Proteasome assembly chaperone 1

Gene ID: 8624, 9606

UniProt: O95456