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FAIM antibody (Internal Region)

FAIM Reactivity: Human, Mouse, Rat, Dog WB, IHC (p) Host: Goat Polyclonal unconjugated
Catalog No. ABIN375120
  • Target See all FAIM Antibodies
    FAIM (Fas Apoptotic Inhibitory Molecule (FAIM))
    Binding Specificity
    • 15
    • 9
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 47
    • 18
    • 16
    • 14
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Dog
    Host
    • 60
    • 2
    Goat
    Clonality
    • 62
    Polyclonal
    Conjugate
    • 21
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FAIM antibody is un-conjugated
    Application
    • 30
    • 26
    • 13
    • 13
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody reacts to all reported isoforms of FAIM1.
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, Rat, Canine.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography
    Immunogen
    Peptide with sequence C-KKYMEDRSKTTN, from the internal region of the protein sequence
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    Discover our top product FAIM Primary Antibody
  • Application Notes
    Peptide ELISA: 1/32000. Western Blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections: 2 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0,5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    FAIM (Fas Apoptotic Inhibitory Molecule (FAIM))
    Alternative Name
    FAIM (FAIM Products)
    Synonyms
    FAIM1 antibody, FAIM antibody, faim antibody, zgc:92712 antibody, zgc:92723 antibody, Fas apoptotic inhibitory molecule antibody, Fas apoptotic inhibitory molecule L homeolog antibody, Fas apoptotic inhibitory molecule b antibody, Fas apoptotic inhibitory molecule a antibody, FAIM antibody, Faim antibody, faim antibody, faim.L antibody, Tsp_00038 antibody, faimb antibody, faima antibody
    Background
    FAIM1 (or Fas Apoptotic Inhibitory Molecule 1) is a recently discovered negative regulator of apoptosis. FAIM1 has no significant regions of homology to other gene products that modulate Fas killing. It plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells. Overexpression of FAIM1 diminishes sensitivity to Fas mediated apoptosis of B and non B cell lines. FAIM1 is highly evolutionarily conserved and is widely expressed in murine tissues, suggesting that FAIM1 plays an important role in cellular physiology.Synonyms: FAIM-1, FAIM1, Fas Apoptotic Inhibitory Molecule 1
    Gene ID
    55179, 9606
    UniProt
    Q9NVQ4
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