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CST3 antibody (Internal Region)

CST3 Reactivity: Human WB Host: Goat Polyclonal unconjugated
Catalog No. ABIN375142
  • Target See all CST3 Antibodies
    CST3 (Cystatin C (CST3))
    Binding Specificity
    • 32
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 113
    • 37
    • 28
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 95
    • 39
    • 13
    • 6
    • 2
    Goat
    Clonality
    • 113
    • 42
    Polyclonal
    Conjugate
    • 84
    • 19
    • 11
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CST3 antibody is un-conjugated
    Application
    • 102
    • 67
    • 41
    • 17
    • 17
    • 16
    • 14
    • 13
    • 10
    • 9
    • 9
    • 8
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    C-SVEEEGVRRA LD
    Specificity
    This antibodyrecognizes CST3 / cystatin C.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    Immunogen
    Peptide with sequence from the internal region of the protein sequence according to NP_000090.1. Genename: CST3
    Top Product
    Discover our top product CST3 Primary Antibody
  • Application Notes
    Peptide ELISA: 1/8000. Western Blot: 0.3 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CST3 (Cystatin C (CST3))
    Alternative Name
    Cystatin-C (CST3 Products)
    Synonyms
    armd11 antibody, fb51d07 antibody, wu:fb24g06 antibody, wu:fb51d07 antibody, wu:fc55f03 antibody, zgc:136227 antibody, ARMD11 antibody, CysC antibody, CYSC antibody, cystatin C antibody, cystatin C L homeolog antibody, cystatin C (amyloid angiopathy and cerebral hemorrhage) antibody, cystatin 3 antibody, CST3 antibody, cst3.L antibody, cst3 antibody, cystatin 3 antibody, Cst3 antibody
    Background
    Cystatins are a superfamily of cysteine proteinase inhibitors found in both plants and animals. The cystatin superfamily encompasses proteins that contain multiple cystatin like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. Cystatin C (Cystatin 3) , a secreted molecule of this family, is of interest from biochemical, medicine and evolutionary points of view. Cystatin C, with molecular weight of 13260 Da, is composed of 120 amino acids, lacks carbohydrate and has two disulfide bridges located near the carboxyl terminus. Cystatin C is increased in patients with malignant diseases, and is related to the insufficiency of renal function and appears to be a better marker than creatinine. On the other hand, low levels of cystatin C involve cause the breakdown of the elastic laminae and, subsequently, the atherosclerosis and abdominal aortic aneurysm.Synonyms: CST3, Cystatin C, Cystatin-3, Gamma-trace, Neuroendocrine basic polypeptide, Post-gamma-globulin
    Gene ID
    1471
    NCBI Accession
    NP_000090
    UniProt
    P01034
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