alpha 2 Antiplasmin antibody (Internal Region)

Catalog No. ABIN375144

Product Details anti-alpha 2 Antiplasmin Antibody

Target: alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))

Binding Specificity: Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This alpha 2 Antiplasmin antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequence: C-KDFLQSLKGF PRGDK

Specificity: This antibody is expected to recognise both reported isoforms (NP_000925.2, NP_001159393.1). Reported variants represent identical protein (NP_000925.2, NP_001159392.1).

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_000925.2, NP_001159393.1. Genename: SERPINF2

Application Details

Application Notes: Peptide ELISA: 1/16000. Western Blot: 0.3 - 1 μg/mL. Immunohistochemistry on paraffin sections: 3 - 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for alpha 2 Antiplasmin

Target: alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))

Alternative Name: alpha-2-Antiplasmin / SERPINF2 (SERPINF2 Products)

Synonyms: A2AP antibody, AAP antibody, ALPHA-2-PI antibody, API antibody, PLI antibody, serpin antibody, AI747498 antibody, Pli antibody, Serpimf2 antibody, serpinf2 antibody, serpinf2l antibody, wu:fd57d08 antibody, Dmrs91 antibody, Pedf antibody, serpin family F member 2 antibody, serpin family F member 1 antibody, serine (or cysteine) peptidase inhibitor, clade F, member 2 antibody, serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a antibody, SERPINF2 antibody, Serpinf2 antibody, SERPINF1 antibody, serpinf2a antibody, Serpinf1 antibody

Background: Alpha 2 Antiplasmin is a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. The protein has a major role in regulating the blood clotting pathway. Mutations result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: AAP, Alpha-2-AP, Alpha-2-PI, Alpha-2-plasmin inhibitor, PLI, Serpin F2

Gene ID: 5345, 9606

UniProt: P08697

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones