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FGFR2 antibody (Fibroblast Growth Factor Receptor 2) (Internal Region)

Details for Product anti-FGFR2 Antibody No. ABIN375199, Supplier: Log in to see
Antigen
  • FGFR2
  • FGFR2IIIb
  • bek
  • bfr-1
  • cd332
  • cek3
  • cfd1
  • ect1
  • fgfr-2
  • jws
  • k-sam
  • kgfr
  • tk14
  • tk25
  • xfgfr2
  • DKFZp469H1521
  • BBDS
  • BEK
  • BFR-1
  • CD332
  • CEK3
  • CFD1
  • ECT1
  • JWS
  • K-SAM
  • KGFR
  • TK14
  • TK25
  • AU043015
  • AW556123
  • Bek
  • Fgfr-2
  • Fgfr-7
  • Fgfr7
  • KGFRTr
  • svs
  • FGF-R
  • fgfr72IIIb
  • FGFR
  • fc56c05
  • wu:fc56c05
  • fibroblast growth factor receptor 2
  • FGFR2
  • fgfr2
  • Fgfr2
Alternatives
anti-Human FGFR2 antibody for Immunohistochemistry
Epitope
Internal Region
25
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14
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8
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5
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
296
79
62
12
4
4
3
3
2
2
2
2
1
1
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1
Host
Goat
196
88
13
2
Clonality
Polyclonal
Conjugate
This FGFR2 antibody is un-conjugated
12
11
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9
5
5
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4
2
2
1
1
1
1
1
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Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
198
120
113
96
67
50
16
11
9
7
4
4
1
1
1
1
Options
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Immunogen Peptide with sequence C-GREKEITASPDY, from the internal region of the protein sequence
Specificity This antibody reacts to FGFR2.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.
Purification Ammonium sulphate precipitation followed by antigen affinity chromatography
Alternative Name CD332 / FGFR-2 (FGFR2 Antibody Abstract)
Background Fibroblast growth factors (FGFs) are members of a large family of structurally related polypeptides that are potent physiological regulators of growth and differentiation for a wide variety of cells of mesodermal, ectodermal and endodermal origin. Four genes encoding for high affinity cell surface FGF receptors (FGFRs) have been identified: FGFR1, FGFR2, FGFR3 and FGFR4. FGFRs are members of the tyrosine kinase family of growth factor receptors. FGFR2 is highly expressed in developing human tissues including the brain, choroids plexus, lung etc.Synonyms: BEK, FGFR2, Fibroblast growth factor receptor 2, KGFR, KSAM, Keratinocyte growth factor receptor 2
Gene ID 2263
NCBI Accession NP_000132
UniProt P21802
Research Area Growth Factors, Receptors
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Application Notes ELISA: 1/64000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-FGFR2 antibody (Fibroblast Growth Factor Receptor 2) (Internal Region) (ABIN375199) anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (Internal Region) antibody
Product cited in: McGrath, Lee, Buring, Hunter, De Vivo: "Novel breast cancer risk alleles and endometrial cancer risk." in: International journal of cancer, Vol. 123, Issue 12, pp. 2961-4, 2008 (PubMed).