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MutY Homolog (E. Coli) (MUTYH) (C-Term) antibody

Details for Product No. ABIN375216, Supplier: Log in to see
Antigen
  • 5730495A01Rik
  • CYP2C
  • MGC145569
  • MUTYH
  • Mutyha
  • Mutyhalpha
  • Mutyhb
  • Mutyhbeta
  • Mutyhc
  • Myh
  • MYH
Alternatives
anti-Human MutY Homolog (E. Coli) antibody for Western Blotting
Epitope
C-Term
16
7
5
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
97
44
38
2
2
Host
Goat
75
15
7
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
76
40
22
21
11
10
8
5
3
2
2
1
1
Supplier
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Immunogen Peptide with sequence C-HISTDAHSLNSAAQ, from the C Terminus of the protein sequence
Specificity This antibody reacts to MUTYH.
Purification Affinity chromatography
Alternative Name MUTYH (MUTYH Antibody Abstract)
Background MYH is the eukaryotic homolog to the E. coli protein MutY. It was first identified in HeLa cells and nicks DNA replication errors, specifically A/G mismatches. MYH is involved in oxidative DNA damage repair. It initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. It possesses both adenine and 2-OH-A DNA glycosylase activities.Synonyms: A/G-specific adenine DNA glycosylase, MYH, MutY homolog
Gene ID 4595
NCBI Accession NP_001041636
UniProt Q9UIF7
Pathways DNA Damage Repair
Application Notes Peptide ELISA: 1/16000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0,5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-MutY Homolog (E. Coli) (MUTYH) (C-Term) antibody (ABIN375216) anti-MutY Homolog (E. Coli) (MUTYH) (C-Term) antibody
Background publications Slupska, Baikalov, Luther, Chiang, Wei, Miller: "Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage." in: Journal of bacteriology, Vol. 178, Issue 13, pp. 3885-92, 1996 (PubMed).