MUTYH antibody (C-Term)

Catalog No. ABIN375216

Product Details anti-MUTYH Antibody

Target: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Binding Specificity: C-Term

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This MUTYH antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to MUTYH.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-HISTDAHSLNSAAQ, from the C Terminus of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/16000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MUTYH

Target: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Alternative Name: MUTYH (MUTYH Products)

Synonyms: MUTYH antibody, MGC145569 antibody, CYP2C antibody, MYH antibody, 5730495A01Rik antibody, Mutyha antibody, Mutyhalpha antibody, Mutyhb antibody, Mutyhbeta antibody, Mutyhc antibody, Myh antibody, mutY DNA glycosylase antibody, mutY homolog (E. coli) antibody, A/G-specific adenine DNA glycosylase-like antibody, MUTYH antibody, mutyh antibody, LOC100373318 antibody, Mutyh antibody

Background: MYH is the eukaryotic homolog to the E. coli protein MutY. It was first identified in HeLa cells and nicks DNA replication errors, specifically A/G mismatches. MYH is involved in oxidative DNA damage repair. It initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. It possesses both adenine and 2-OH-A DNA glycosylase activities.Synonyms: A/G-specific adenine DNA glycosylase, MYH, MutY homolog

Gene ID: 4595

NCBI Accession: NP_001041636

UniProt: Q9UIF7

Pathways: DNA Damage Repair