SLC10A2
Reactivity: Mouse, Human
WB, ELISA, IP
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Peptide ELISA: 1/32000. Western Blot: 0.5 - 1.5 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
zgc:63998 antibody, ISBAT antibody, ASBT antibody, IBAT antibody, ISBT antibody, NTCP2 antibody, PBAM antibody, solute carrier family 10 member 2 antibody, solute carrier family 10 (sodium/bile acid cotransporter), member 2 antibody, solute carrier family 10, member 2 antibody, SLC10A2 antibody, slc10a2 antibody, Slc10a2 antibody
Background
This gene encodes a sodium/bile acid cotransporter. This transporter is the primarymechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM), muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq]Synonyms: ASBT, Apical sodium-dependent bile acid transporter, IBAT, ISBT, Ileal Na(+)/bile acid cotransporter, Ileal sodium-dependent bile acid transporter, Ileal sodium/bile acid cotransporter, NTCP2, Na(+)-dependent ileal bile acid transporter, Sodium/taurocholate cotransporting polypeptide, Solute carrier family 10 member 2, ileal