SLC10A2 antibody (C-Term)

Catalog No. ABIN375244

Product Details anti-SLC10A2 Antibody

Target: SLC10A2 (Solute Carrier Family 10 (Sodium/bile Acid Cotransporter Family), Member 2 (SLC10A2))

Binding Specificity: C-Term

Reactivity: Mouse, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This SLC10A2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-DETNKGFQPD EK

Specificity: This antibody SLC0A2 at C-term.

Cross-Reactivity (Details): Species reactivity (expected):Rat.
Species reactivity (tested):Mouse.

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic peptide with sequence C-DETNKGFQPDEK, from the C-Terminus of Mouse SLC10A2 (NP_035518.1). Genename: SLC10A2

Application Details

Application Notes: Peptide ELISA: 1/32000. Western Blot: 0.5 - 1.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SLC10A2

Target: SLC10A2 (Solute Carrier Family 10 (Sodium/bile Acid Cotransporter Family), Member 2 (SLC10A2))

Alternative Name: SLC10A2 (SLC10A2 Products)

Synonyms: zgc:63998 antibody, ISBAT antibody, ASBT antibody, IBAT antibody, ISBT antibody, NTCP2 antibody, PBAM antibody, solute carrier family 10 member 2 antibody, solute carrier family 10 (sodium/bile acid cotransporter), member 2 antibody, solute carrier family 10, member 2 antibody, SLC10A2 antibody, slc10a2 antibody, Slc10a2 antibody

Background: This gene encodes a sodium/bile acid cotransporter. This transporter is the primarymechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM), muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq]Synonyms: ASBT, Apical sodium-dependent bile acid transporter, IBAT, ISBT, Ileal Na(+)/bile acid cotransporter, Ileal sodium-dependent bile acid transporter, Ileal sodium/bile acid cotransporter, NTCP2, Na(+)-dependent ileal bile acid transporter, Sodium/taurocholate cotransporting polypeptide, Solute carrier family 10 member 2, ileal

Molecular Weight: 38.1 kDa according to NP_035518.1.

Gene ID: 20494

NCBI Accession: NP_035518

UniProt: P70172