beta Actin antibody

Catalog No. ABIN387755

Product Details anti-beta Actin Antibody

Target: beta Actin (ACTB) (Actin, beta (ACTB))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This beta Actin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: ACTB recombinant protein is used to produce this monoclonal antibody.

Clone: 8H10D10

Isotype: IgG

Application Details

Application Notes: WB: 1:4000-1:8000. WB: 1:1000. WB: 1:1000. IHC: 1:50. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-beta Actin antibody (ABIN387755)

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Wu, Wu, Ma, Shao, Tan, Tan, Gu, Zhou, Sun, Sun, Wu, Xu: "CUG-binding protein 1 regulates HSC activation and liver fibrogenesis." in: Nature communications, Vol. 7, pp. 13498, (2018) (PubMed).

Park, Shin: "Metformin alleviates ageing cellular phenotypes in Hutchinson-Gilford progeria syndrome dermal fibroblasts." in: Experimental dermatology, Vol. 26, Issue 10, pp. 889-895, (2018) (PubMed).

Tang, Hu, Yang, Xue, Gong, Sun, Shi, Zhang, Li, Yang, Zhang, Xie: "SBI0206965, a novel inhibitor of Ulk1, suppresses non-small cell lung cancer cell growth by modulating both autophagy and apoptosis pathways." in: Oncology reports, Vol. 37, Issue 6, pp. 3449-3458, (2018) (PubMed).

Zhang, Li, Huang, Guan, Zhu: "Overexpression of ubiquitin specific peptidase 14 predicts unfavorable prognosis in esophageal squamous cell carcinoma." in: Thoracic cancer, Vol. 8, Issue 4, pp. 344-349, (2018) (PubMed).

Seong, Seo, Kim, Fletcher, Morgan, Kumar, Choi, Shin: "Schlafen 14 (SLFN14) is a novel antiviral factor involved in the control of viral replication." in: Immunobiology, Vol. 222, Issue 11, pp. 979-988, (2018) (PubMed).

Rong, Huang, Liu, Wei: "Protective Effects of Geniposide on Hepatic Ischemia/Reperfusion Injury." in: Transplantation proceedings, Vol. 49, Issue 6, pp. 1455-1460, (2018) (PubMed).

Zhu, Wang, Zhou, Zhou, Cheng, Liu, Wang, Chen, Chen, Luo, Hua: "PML-RARα stabilized by zinc in human acute promyelocytic leukemia NB4 cells." in: Journal of inorganic biochemistry, Vol. 175, pp. 92-100, (2018) (PubMed).

Hu, Yang, Fan, Wang, Zhao, Zha, Zhang, Tu: "Huaier aqueous extract sensitizes cells to rapamycin and cisplatin through activating mTOR signaling." in: Journal of ethnopharmacology, Vol. 186, pp. 143-150, (2017) (PubMed).

Wang, Tang, Hu, Wang, Gong, Sun, Xie: "HDAC6 promotes cell proliferation and confers resistance to gefitinib in lung adenocarcinoma." in: Oncology reports, Vol. 36, Issue 1, pp. 589-97, (2017) (PubMed).

Chen, Wang, Tian, Hu, Xu, Yang, Wang: "12b-hydroxy-des-D-garcigerin A enhances glucose metabolism in insulin-resistant HepG2 cells via the IRS-1/PI3-K/Akt cell signaling pathway." in: Journal of Asian natural products research, Vol. 18, Issue 11, pp. 1091-100, (2017) (PubMed).

Liška, Chylíková, Janků, Šeda, Vernerová, Pravenec, Křen: "Splicing mutation in Sbf1 causes nonsyndromic male infertility in the rat." in: Reproduction (Cambridge, England), Vol. 152, Issue 3, pp. 215-23, (2017) (PubMed).

Yang, Fan, Zhao, Zha, Zhang, Hu, Tu: "Huaier aqueous extract inhibits proliferation and metastasis of tuberous sclerosis complex cell models through downregulation of JAK2/STAT3 and MAPK signaling pathways." in: Oncology reports, Vol. 36, Issue 3, pp. 1491-8, (2017) (PubMed).

Lv, Wu, Mu, Liu, Yan, Xu, Wu, Du, Yu, Mu: "Insulin-like growth factor 1 promotes the proliferation and committed differentiation of human dental pulp stem cells through MAPK pathways." in: Archives of oral biology, Vol. 72, pp. 116-123, (2017) (PubMed).

Birkenmeier, Hemdan, Kurz, Bigl, Pieroh, Debebe, Buchold, Thieme, Wichmann, Dehghani: "Ethyl Pyruvate Combats Human Leukemia Cells but Spares Normal Blood Cells." in: PLoS ONE, Vol. 11, Issue 8, pp. e0161571, (2017) (PubMed).

Niu, Huang, Zhang, Zhang, Chen, Sun, Ding, Liao: "Deletion of autophagy-related gene 7 in dopaminergic neurons prevents their loss induced by MPTP." in: Neuroscience, Vol. 339, pp. 22-31, (2017) (PubMed).

Zhang, Wang, Hu: "STARD13 promotes hepatocellular carcinoma apoptosis by acting as a ceRNA for Fas." in: Biotechnology letters, Vol. 39, Issue 2, pp. 207-217, (2017) (PubMed).

Li, Shen, Jiang, Shen, You, Sun, Xu, Hu, Wu, Wang: "Anti-Inflammatory Effects of Chloranthalactone B in LPS-Stimulated RAW264.7 Cells." in: International journal of molecular sciences, Vol. 17, Issue 11, (2017) (PubMed).

Pan, Wang, Zhu, Xing, Cui, Li, Yu, Wang, Zhu, Ye, Wu, Wang, Lu: "STAT3 signaling drives EZH2 transcriptional activation and mediates poor prognosis in gastric cancer." in: Molecular cancer, Vol. 15, Issue 1, pp. 79, (2017) (PubMed).

Target Details for beta Actin

Target: beta Actin (ACTB) (Actin, beta (ACTB))

Alternative Name: Beta-actin (ACTB Products)

Synonyms: BRWS1 antibody, PS1TP5BP1 antibody, ACTA1 antibody, Actx antibody, E430023M04Rik antibody, beta-actin antibody, ps1tp5bp1 antibody, act-2 antibody, actb antibody, B-actin antibody, LOC100174883 antibody, LOC100304816 antibody, A antibody, ACT5C antibody, Ac5C antibody, Act antibody, Act-5C antibody, Act5 antibody, Act5c antibody, Actin antibody, Actin/BAP47 antibody, Actin5C antibody, BAP47 antibody, Bap47 antibody, CG4027 antibody, Dmel\\CG4027 antibody, M32055 antibody, T11 antibody, act antibody, act 5C antibody, act5C antibody, actin antibody, actin5C antibody, anon-EST:fe2D2 antibody, beta-actin/Bap47 antibody, cyt5C antibody, l(1)G0009 antibody, l(1)G0010 antibody, l(1)G0025 antibody, l(1)G0079 antibody, l(1)G0117 antibody, l(1)G0177 antibody, l(1)G0245 antibody, l(1)G0330 antibody, l(1)G0420 antibody, l(1)G0486 antibody, Bact antibody, ACT-5 antibody, ACTB antibody, B-ACTZF antibody, actba antibody, bact antibody, bactin1 antibody, bactzf antibody, wu:fd18f05 antibody, A26C1B antibody, POTE2alpha antibody, POTEACTIN antibody, Beta-actin antibody, actin beta antibody, actin, beta antibody, cytoplasmic actin OlCA1 antibody, beta-actin antibody, Actin 5C antibody, actin gamma 1 antibody, actin, beta 1 antibody, actin, beta L homeolog antibody, beta actin antibody, POTE ankyrin domain family member F antibody, actin, beta like 2 antibody, actin, cytoplasmic 1 antibody, ACTB antibody, Actb antibody, actb antibody, LOC100174883 antibody, LOC100304816 antibody, Act5C antibody, ACTG1 antibody, actb1 antibody, actb.L antibody, LOC100136352 antibody, POTEF antibody, ACTBL2 antibody, LOC109073280 antibody

Background: This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins.

Molecular Weight: 41737

Gene ID: 60

NCBI Accession: NP_001092

UniProt: P60709

Pathways: Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Maintenance of Protein Location, Phototransduction