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FIGF antibody (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D)) (C-Term)

Details for Product anti-Figf Antibody No. ABIN387760, Supplier: Login to see
Antigen
  • FIGF
  • vegfd
  • vegf-d
  • VEGFD
  • AI325264
  • VEGF-D
  • Vegfd
  • Vegf-d
Alternatives
anti-Human FIGF antibody for Enzyme Immunoassay
Epitope
C-Term, N-Term
24
17
14
12
8
8
8
8
6
3
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
111
15
15
6
1
1
1
Host
Mouse
104
15
2
2
Clonality (Clone)
Monoclonal ()
Conjugate
This FIGF antibody is un-conjugated
9
8
7
4
4
4
1
1
Application
Western Blotting (WB)
94
60
50
13
5
4
3
3
1
Supplier
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Immunogen This monoclonal antibody is generated from mice immunized with three KLH conjugated synthetic peptides corresponding to N-terminal, central, and C-terminal sequences of human VEGF4.
Clone 28AT743-288-48
Isotype IgG1
Specificity This monoclonal antibody is generated from mice immunized with three KLH conjugated synthetic peptides corresponding to N-terminal, central, and C-terminal sequences of human VEGF4.
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.
Alternative Name VEGF4 (Figf Antibody Abstract)
Background The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C.
Synonyms: Vascular Endothelial Growth Factor D, c-fos-induced growth factor, FIGF, VEGFD, VEGF-D, VEGF4
Molecular Weight 40444 DA
Gene ID 2277
UniProt O43915
Research Area Cell Signaling, Cell Structure, Cancer, Cell Cycle
Pathways RTK Signaling
Application Notes WB = 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-FIGF antibody (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D)) (C-Term) (ABIN387760) The anti-VEGF4 Mab (ABIN387760) is used in Western blot to detect VEGF4 in HDMEC cell...
Product cited in: Pfannschmidt, Bade, Hoheisel et al.: "Identification of immunohistochemical prognostic markers for survival after resection of pulmonary metastases from colorectal carcinoma." in: The Thoracic and cardiovascular surgeon, Vol. 57, Issue 7, pp. 403-8, 2009 (PubMed).

Background publications Romero, Friel, Velez Edwards et al.: "A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM)." in: American journal of obstetrics and gynecology, Vol. 203, Issue 4, pp. 361.e1-361.e30, 2010 (PubMed).

Deguchi, Ichikawa, Soga et al.: "Clinical significance of vascular endothelial growth factors C and D and chemokine receptor CCR7 in gastric cancer." in: Anticancer research, Vol. 30, Issue 6, pp. 2361-6, 2010 (PubMed).

Romero, Velez Edwards, Kusanovic et al.: "Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes." in: American journal of obstetrics and gynecology, Vol. 202, Issue 5, pp. 431.e1-34, 2010 (PubMed).

Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

Becker, Pavlakovic, Ludewig et al.: "Neuroblastoma progression correlates with downregulation of the lymphangiogenesis inhibitor sVEGFR-2." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 5, pp. 1431-41, 2010 (PubMed).