You are viewing an incomplete version of our website. Please click to reload the website as full version.

Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (N-Term) antibody

Details for Product No. ABIN387778, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms kmt1a, suv39h, H3-K9-HMTase 1, KMT1A, MG44, SUV39H, AI852103, AL022883, DXHXS7466e, mIS6, RGD1565028, fe02c04, suv39h1, wu:fe02c04, zgc:101027
(48), (15), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Human, Mouse (Murine)
(90), (32), (20), (2), (2), (1), (1)
(72), (19)
Clonality (Clone)
Monoclonal ()
(6), (6), (6), (5), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(72), (46), (16), (11), (11), (7), (4), (2), (2), (2)
Pubmed 5 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 400 μL
Shipping to United States ( )
Availability Will be delivered in 2 to 4 Business Days
Immunogen This SUV39H1 antibody was raised using purified recombinant GST fusion protein encoding N-terminal of human SUV39H1.
Clone 42AT239-96-72
Isotype IgG1
Specificity This SUV39H1 antibody was raised using purified recombinant GST fusion protein encoding N-terminal of human SUV39H1.
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.
Alternative Name SUV39H1 (SUV39H1 Antibody Abstract)
Background This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression.
Synonyms: Histone-lysine N-methyltransferase, H3 lysine-9 specific 1, Suppressor of variegation 3-9 homolog 1, KMT1A
Molecular Weight 47907 DA
Gene ID 6839
NCBI Accession NP_003164
Research Area Signaling, Protein Modifications, Cancer, Chromatin, Cell Structure
Application Notes WB = 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 0.4 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (N-Term) antibody (ABIN387778) Western analysis of extracts from 293 cells using SUV39H1 antibody.
Background publications Chen, Li, Zwolinska et al.: "MDM2 recruitment of lysine methyltransferases regulates p53 transcriptional output." in: The EMBO journal, Vol. 29, Issue 15, pp. 2538-52, 2010 (PubMed).

Goyama, Nitta, Yoshino et al.: "EVI-1 interacts with histone methyltransferases SUV39H1 and G9a for transcriptional repression and bone marrow immortalization." in: Leukemia, Vol. 24, Issue 1, pp. 81-8, 2010 (PubMed).

Cherrier, Suzanne, Redel et al.: "p21(WAF1) gene promoter is epigenetically silenced by CTIP2 and SUV39H1." in: Oncogene, Vol. 28, Issue 38, pp. 3380-9, 2009 (PubMed).

Li, Chen, Kabra et al.: "Inhibition of SUV39H1 methyltransferase activity by DBC1." in: The Journal of biological chemistry, Vol. 284, Issue 16, pp. 10361-6, 2009 (PubMed).

Spensberger, Delwel: "A novel interaction between the proto-oncogene Evi1 and histone methyltransferases, SUV39H1 and G9a." in: FEBS letters, Vol. 582, Issue 18, pp. 2761-7, 2008 (PubMed).

Catalog No. ABIN387778
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)