|+1 404 474 4654|
|+1 888 205 9894 (TF)|
conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) antibody
|Synonyms||IKK1, IKKA, IKBKA, TCF16, NFKBIKA, IKK-alpha, Ikka, Chuk1, Fbx24, Fbxo24, AI256658, MGC25325, CHUK, chuk, MGC83432, DKFZp459O053|
Alternatives Western Blotting (WB), ELISA
|5 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Alternative name||IKK alpha|
|Immunogen||This antibody was raised using purified His-tagged recombinant full length human IKK alpha.|
|Description||Other names: Inhibitor of nuclear factor kappa-B kinase alpha subunit, I kappa-B kinase alpha, IkBKA, IKK-A, IkappaB kinase, I-kappa-B kinase 1, IKK1, Conserved helix-loop-helix ubiquitous kinase, Nuclear factor NFkappaB inhibitor kinase alpha, NFKBIKA|
|Characteristics||Purified Mouse Monoclonal Antibody (Mab)|
|Specificity||This IKK alpha antibody was raised using purified His-tagged recombinant full length human IKK alpha.|
Background: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
|Application Notes||The suggested dilution will be: ELISA 1:1,000 Western blotting 1:100~500|
|Buffer||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Research Area||Phospho-specific antibodies, Cell Signaling, Protein Modifications, Transcription Factors, Signaling, Cell Structure|
|Restrictions||For Research Use only|
|The anti-IKKalpha Mab (Cat. #ABIN387825) is used in Western blot to detect IKKalpha in HeLa cell lysate.|
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Li, Morgan, Choksi et al.: "MicroRNAs modulate the noncanonical transcription factor NF-kappaB pathway by regulating expression of the kinase IKKalpha during macrophage differentiation." in: Nature immunology, Vol. 11, Issue 9, pp. 799-805, 2010 (PubMed).