You are viewing an incomplete version of our website. Please click to reload the website as full version.

DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 31-61), (N-Term) antibody

Details for Product No. ABIN387883, Supplier: Log in to see
Antigen
  • DNMT3A
  • DNMT3A2
  • M.HsaIIIA
  • MmuIIIA
Epitope
AA 31-61, N-Term
41
22
16
15
14
14
12
9
7
7
7
4
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
200
55
35
3
2
2
2
1
1
1
1
1
1
1
1
Host
Rabbit
186
16
2
2
1
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
13
11
11
8
8
8
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
170
97
55
23
14
11
11
8
6
4
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen This Dnmt3a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-61 AA from the N-terminal region of human Dnmt3a.
Clone RB15267
Isotype Ig
Specificity This Dnmt3a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39~68 amino acids from the N-terminal region of human Dnmt3a.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name DNMT3A (DNMT3A Antibody Abstract)
Background CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3a is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
Synonyms: DNA (cytosine-5)-methyltransferase 3A, Dnmt3a, DNA methyltransferase HsaIIIA, DNA MTase HsaIIIA, M.HsaIIIA
Molecular Weight 101558 DA
Gene ID 1788
UniProt Q9Y6K1
Research Area Signaling, Protein Modifications, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 31-61), (N-Term) antibody (ABIN387883) Western blot analysis of anti-Dnmt3a Antibody (N-term R46) (ABIN387883) in Jurkat cel...
Immunohistochemistry (IHC) image for anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 31-61), (N-Term) antibody (ABIN387883) Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with Dnmt3a ...
Background publications Xie, Wang, Okano et al.: "Cloning, expression and chromosome locations of the human DNMT3 gene family." in: Gene, Vol. 236, Issue 1, pp. 87-95, 1999 (PubMed).

Robertson, Uzvolgyi, Liang et al.: "The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors." in: Nucleic acids research, Vol. 27, Issue 11, pp. 2291-8, 1999 (PubMed).