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KDM2A antibody (Lysine (K)-Specific Demethylase 2A) (AA 500-527)

Details for Product anti-KDM2A Antibody No. ABIN387896, Supplier: Log in to see
Antigen
  • 5530401A10Rik
  • 100043628
  • AA589516
  • AW536790
  • CXXC8
  • Cxxc8
  • Fbl7
  • FBL7
  • Fbl11
  • FBL11
  • FBXL11
  • Fbxl11
  • Gm4560
  • Jhdm1
  • JHDM1A
  • Jhdm1a
  • KDM2A
  • lalina
  • LILINA
Epitope
AA 500-527, Center
15
8
5
5
2
2
2
2
1
1
1
1
Reactivity
Human
54
19
18
4
3
1
1
1
Host
Rabbit
39
12
3
Clonality (Clone)
Polyclonal ()
Conjugate
This KDM2A antibody is un-conjugated
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
40
18
12
10
8
4
2
2
1
1
Supplier
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Immunogen This JHDM1a/FBXL11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 500-527 AA from the Central region of human JHDM1a/FBXL11.
Clone RB14392
Isotype Ig
Specificity This JHDM1a/FBXL11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 506~536 amino acids from the Center of human JHDM1a/FBXL11.
Predicted Reactivity Mouse (Murine)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name JHDM1a/FBXL11 (KDM2A Antibody Abstract)
Background JHDM1a/FBXL11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box),which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least 6 highly degenerated leucine-rich repeats.
Synonyms: JmjC domain-containing histone demethylation protein 1A, [Histone-H3]-lysine-36 demethylase 1A, F-box/LRR-repeat protein 11, F-box and leucine-rich repeat protein 11, F-box protein FBL7, F-box protein Lilina, CXXC-type zinc finger protein 8, FBXL11
Molecular Weight 132793 DA
Gene ID 22992
UniProt Q9Y2K7
Research Area Signaling, Protein Modifications, Cell Structure
Application Notes IHC (p) = 1:10-50, WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Immunohistochemistry (IHC) image for anti-KDM2A antibody (Lysine (K)-Specific Demethylase 2A) (AA 500-527) (ABIN387896) Formalin-fixed and paraffin-embedded human testis tissue reacted with JHDM1a/FBXL11 a...
Western Blotting (WB) image for anti-KDM2A antibody (Lysine (K)-Specific Demethylase 2A) (AA 500-527) (ABIN387896) Western blot analysis of JHDM1a/FBXL11 (arrow) using rabbit polyclonal JHDM1a/FBXL11 ...
Western Blotting (WB) image for anti-KDM2A antibody (Lysine (K)-Specific Demethylase 2A) (AA 500-527) (ABIN387896) JHDM1a/FBXL11 Antibody (Center) (ABIN387896) western blot analysis in Jurkat cell lin...
Background publications Tsukada, Fang, Erdjument-Bromage, Warren, Borchers, Tempst, Zhang: "Histone demethylation by a family of JmjC domain-containing proteins." in: Nature, Vol. 439, Issue 7078, pp. 811-6, 2006

Andersen, Lam, Leung, Ong, Lyon, Lamond, Mann: "Nucleolar proteome dynamics." in: Nature, Vol. 433, Issue 7021, pp. 77-83, 2005