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Histone Cluster 3, H3 (HIST3H3) (AA 1-30), (meLys9) antibody

Details for Product No. ABIN387902, Supplier: Login to see
Antigen
  • H3.4
  • H3/g
  • H3FT
  • H3t
  • CG33848
  • Dmel\CG33848
  • H3.2-221
  • Hist1
  • H3/i
  • H3FI
  • h3
  • Hist1h3f
  • hist2h3c
  • T6J4.12
  • T6J4_12
Epitope
AA 1-30, meLys9
113
107
76
55
51
39
35
34
33
31
29
28
27
25
25
24
23
23
22
20
20
19
18
18
17
16
16
16
16
16
15
14
14
13
13
13
13
12
11
11
10
10
10
9
9
9
9
8
7
7
7
7
6
6
6
6
5
5
5
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
1214
564
505
166
41
36
35
28
26
17
14
12
9
7
4
4
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Host
Rabbit
1068
193
17
12
1
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
35
28
27
24
21
21
18
15
15
10
10
10
10
10
10
4
Application
Dot Blot (DB)
1032
366
304
303
234
228
178
125
109
90
61
55
37
36
16
6
3
2
1
1
1
Supplier
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Immunogen This Histone H3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from human Histone H3.
Clone RB1169
Isotype Ig
Specificity This Histone H3-MeK9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide methylated on K9(2 methyl groups) between 1~30 amino acids from aa 6~12 of human Histone 3.
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.
Alternative Name Histone H3 (HIST3H3 Antibody Abstract)
Background Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene for histone H3-MeK9 is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Synonyms: Histone H3
Molecular Weight 15273 DA
Gene ID 3021
UniProt P84243
Research Area Protein Modifications, Cancer, Chromatin, Signaling, Cell Structure
Pathways
Application Notes DB = 1:500
Restrictions For Research Use only
Format Liquid
Concentration 0.35 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
 image for anti-Histone Cluster 3, H3 (HIST3H3) (AA 1-30), (meLys9) antibody (ABIN387902) Dot blot analysis of anti-Methyl-K-H3-K9(2Me)-4MAPS Pab (ABIN387902) on nitrocellulos...
Background publications Marzluff, Gongidi, Woods et al.: "The human and mouse replication-dependent histone genes." in: Genomics, Vol. 80, Issue 5, pp. 487-98, 2002 (PubMed).

Albig, Doenecke: "The human histone gene cluster at the D6S105 locus." in: Human genetics, Vol. 101, Issue 3, pp. 284-94, 1998 (PubMed).

Albig, Kioschis, Poustka et al.: "Human histone gene organization: nonregular arrangement within a large cluster." in: Genomics, Vol. 40, Issue 2, pp. 314-22, 1997 (PubMed).