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Histone Cluster 3, H3 (HIST3H3) (AA 1-30), (meLys9) antibody

Details for Product No. ABIN387902, Supplier: Log in to see
Antigen
  • H3.4
  • H3/g
  • H3FT
  • H3t
  • CG33848
  • Dmel\CG33848
  • H3.2-221
  • Hist1
  • H3/i
  • H3FI
  • h3
  • Hist1h3f
  • hist2h3c
  • T6J4.12
  • T6J4_12
Epitope
AA 1-30, meLys9
112
108
79
58
49
41
40
35
34
33
33
31
30
29
28
28
27
24
24
23
21
21
20
19
19
18
17
17
16
16
16
16
15
15
14
13
13
13
13
12
12
11
11
10
10
10
10
10
10
10
10
9
9
8
7
7
6
6
6
6
5
5
5
5
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
1356
653
590
194
53
44
36
36
30
28
26
14
11
7
4
4
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Host
Rabbit
1216
186
18
11
1
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
35
28
27
24
21
21
18
15
15
10
10
10
10
10
10
4
1
Application
Dot Blot (DB)
1133
402
393
368
295
224
185
164
125
82
61
58
37
36
16
6
3
2
2
1
1
Supplier
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Immunogen This Histone H3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from human Histone H3.
Clone RB1169
Isotype Ig
Specificity This Histone H3-MeK9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide methylated on K9(2 methyl groups) between 1~30 amino acids from aa 6~12 of human Histone 3.
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.
Alternative Name Histone H3 (HIST3H3 Antibody Abstract)
Background Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene for histone H3-MeK9 is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Synonyms: Histone H3
Molecular Weight 15273 DA
Gene ID 3021
UniProt P84243
Research Area Protein Modifications, Cancer, Chromatin, Signaling, Cell Structure
Application Notes DB = 1:500
Restrictions For Research Use only
Format Liquid
Concentration 0.35 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
 image for anti-Histone Cluster 3, H3 (HIST3H3) (AA 1-30), (meLys9) antibody (ABIN387902) Dot blot analysis of anti-Methyl-K-H3-K9(2Me)-4MAPS Pab (ABIN387902) on nitrocellulos...
Background publications Marzluff, Gongidi, Woods et al.: "The human and mouse replication-dependent histone genes." in: Genomics, Vol. 80, Issue 5, pp. 487-98, 2002 (PubMed).

Albig, Doenecke: "The human histone gene cluster at the D6S105 locus." in: Human genetics, Vol. 101, Issue 3, pp. 284-94, 1998 (PubMed).

Albig, Kioschis, Poustka et al.: "Human histone gene organization: nonregular arrangement within a large cluster." in: Genomics, Vol. 40, Issue 2, pp. 314-22, 1997 (PubMed).