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Histone Cluster 3, H3 (HIST3H3) (AA 1-30), (meLys9) antibody

Details for Product No. ABIN387902, Supplier: Log in to see
Antigen
  • H3.4
  • H3/g
  • H3FT
  • H3t
  • CG33848
  • Dmel\CG33848
  • H3.2-221
  • Hist1
  • H3/i
  • H3FI
  • h3
  • Hist1h3f
  • hist2h3c
  • T6J4.12
  • T6J4_12
  • histone cluster 3, H3
  • zgc:173552
  • CG33848 gene product from transcript CG33848-RA
  • histone cluster 1, H3f
  • histone cluster 1, H3g protein
  • histone H3
  • Histone H3 similar to S. cerevisiae histone H3 genes HHT1 (YBR010W) and HHT2 (YNL031C); almost identical to nonallelic orfs 19.1853 and 19.1061
  • Protein HIS-27
  • similar to CG31613-PA
  • HIST3H3
  • zgc:173552
  • Hist3h3
  • His3:CG33848
  • Hist1h3f
  • HIST1H3F
  • hist1h3g
  • AT1G13370
  • HHT3
  • his-27
  • LOC680498
Epitope
AA 1-30, meLys9
151
144
123
91
89
88
86
82
74
72
70
57
55
53
51
49
48
41
40
36
35
31
30
29
28
26
26
25
24
22
22
21
20
20
20
18
18
16
16
16
16
15
15
15
15
15
15
15
14
13
13
13
13
13
12
11
11
10
10
10
10
9
9
9
8
8
8
8
8
7
7
7
6
6
6
6
5
5
5
5
5
5
4
4
4
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
2233
1504
874
606
188
96
75
75
74
69
67
59
47
40
35
31
28
26
18
8
4
4
4
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Host
Rabbit
1972
338
18
12
1
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
89
77
75
61
61
53
45
45
45
45
45
31
22
22
12
12
12
11
11
11
11
11
11
7
6
6
6
6
4
3
Application
Dot Blot (DB)
1992
990
660
592
554
500
420
227
159
156
153
106
56
37
36
16
7
5
3
3
2
2
1
1
1
1
1
Options
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Immunogen This Histone H3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from human Histone H3.
Clone RB1169
Isotype Ig
Specificity This Histone H3-MeK9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide methylated on K9(2 methyl groups) between 1~30 amino acids from aa 6~12 of human Histone 3.
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.
Alternative Name Histone H3 (HIST3H3 Antibody Abstract)
Background Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene for histone H3-MeK9 is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Synonyms: Histone H3
Molecular Weight 15273 DA
Gene ID 3021
UniProt P84243
Research Area Protein Modifications, Cancer, Chromatin, Signaling, Cell Structure
Application Notes DB = 1:500
Restrictions For Research Use only
Format Liquid
Concentration 0.35 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
 image for anti-Histone Cluster 3, H3 (HIST3H3) (AA 1-30), (meLys9) antibody (ABIN387902) Dot blot analysis of anti-Methyl-K-H3-K9(2Me)-4MAPS Pab (ABIN387902) on nitrocellulos...
Background publications Marzluff, Gongidi, Woods, Jin, Maltais: "The human and mouse replication-dependent histone genes." in: Genomics, Vol. 80, Issue 5, pp. 487-98, 2002 (PubMed).

Albig, Doenecke: "The human histone gene cluster at the D6S105 locus." in: Human genetics, Vol. 101, Issue 3, pp. 284-94, 1998 (PubMed).

Albig, Kioschis, Poustka, Meergans, Doenecke: "Human histone gene organization: nonregular arrangement within a large cluster." in: Genomics, Vol. 40, Issue 2, pp. 314-22, 1997 (PubMed).