K(lysine) Acetyltransferase 5 (KAT5) (AA 33-64), (N-Term) antibody

Details for Product No. ABIN387933, Supplier: Log in to see
Antigen
  • 6121
  • CG6121
  • DmEG0007.7
  • Dmel/TIP60
  • Dmel\\CG6121
  • Dmel\\TIP60
  • EG0007.7
  • EG:EG0007.7
  • TIP60
  • dTIP60
  • dTip60
  • dmHAG405
  • im:6908768
  • wu:fb55b08
  • zgc:110752
  • ESA1
  • HTATIP
  • HTATIP1
  • PLIP
  • TIP
  • ZC2HC5
  • cPLA2
  • AI839539
  • CPLA2
  • Htatip
  • Htatip1
  • Tip55
  • Tip60
  • zgc:92510
  • K(lysine) acetyltransferase 5
  • CG6121 gene product from transcript CG6121-RA
  • histone acetyltransferase Tip60
  • tip60
  • HIV-1 tat interactive protein, homolog (human)
  • zgc:92510
  • LOC100340634
  • Tip60
  • AaeL_AAEL014072
  • Smp_053140
  • htatip
  • KAT5
  • Kat5
Alternatives
anti-Human K(lysine) Acetyltransferase 5 antibody for Chromatin Immunoprecipitation
Epitope
AA 33-64, N-Term
12
10
8
7
7
7
5
5
5
4
4
4
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
167
74
59
9
8
7
7
6
6
5
3
3
2
2
2
1
1
1
1
Host
Rabbit
138
28
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
6
6
6
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
114
77
54
25
21
13
10
6
4
3
2
2
1
1
1
Options
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Immunogen This KAT5 / Tip60/HTATIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-64 AA from the N-terminal region of human KAT5 / Tip60/HTATIP.
Clone RB05776
Isotype Ig
Specificity This KAT5 / Tip60/HTATIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41~71 amino acids from the N-terminal region of human HTATIP.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name KAT5 / Tip60/HTATIP (KAT5 Antibody Abstract)
Background HTATIP belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction.
Synonyms: 60 kDa Tat interactive protein, Tip60, HIV-1 Tat interactive protein, cPLA(2) interacting protein,
Molecular Weight 58582 DA
Gene ID 10524
UniProt Q92993
Research Area Signaling, Cell Signaling, Protein Modifications, Cancer, Transcription Factors, Chromatin, Cell Structure
Pathways Intracellular Steroid Hormone Receptor Signaling Pathway
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 33-64), (N-Term) antibody (ABIN387933) Western blot analysis of anti-HTATIP Pab (ABIN387933) in Jurkat cell line lysates (35...
Western Blotting (WB) image for anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 33-64), (N-Term) antibody (ABIN387933) Western blot analysis of anti-HTATIP Pab(ABIN387933) in mouse liver tissue lysate (35...
Product cited in: Yamagata, Kitabayashi: "Sirt1 physically interacts with Tip60 and negatively regulates Tip60-mediated acetylation of H2AX." in: Biochemical and biophysical research communications, Vol. 390, Issue 4, pp. 1355-60, 2009 (PubMed).

Background publications Cai, Jin, Florens, Swanson, Kusch, Li, Workman, Washburn, Conaway, Conaway: "The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes." in: The Journal of biological chemistry, Vol. 280, Issue 14, pp. 13665-70, 2005 (PubMed).