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HDAC11 antibody (N-Term)

HDAC11 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB2588 unconjugated
Catalog No. ABIN387964
  • Target See all HDAC11 Antibodies
    HDAC11 (Histone Deacetylase 11 (HDAC11))
    Binding Specificity
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    Reactivity
    • 59
    • 43
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 69
    • 5
    Rabbit
    Clonality
    • 70
    • 4
    Polyclonal
    Conjugate
    • 37
    • 7
    • 6
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HDAC11 antibody is un-conjugated
    Application
    • 64
    • 43
    • 32
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This HDAC11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HDAC11.
    Clone
    RB2588
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Janssen, Schmalbach, Boeselt, Sarlette, Dengler, Petri: "Differential histone deacetylase mRNA expression patterns in amyotrophic lateral sclerosis." in: Journal of neuropathology and experimental neurology, Vol. 69, Issue 6, pp. 573-81, (2010) (PubMed).

  • Target
    HDAC11 (Histone Deacetylase 11 (HDAC11))
    Alternative Name
    HDAC11 (HDAC11 Products)
    Synonyms
    CG31119 antibody, DHDACX antibody, Dmel\\CG31119 antibody, HDAC11 antibody, HDACX antibody, dHDAC11 antibody, dmHDA403 antibody, zgc:91942 antibody, HD11 antibody, histone deacetylase 11 antibody, Histone deacetylase 11 antibody, hypothetical protein antibody, HDAC11 antibody, hdac11 antibody, CpipJ_CPIJ001619 antibody, Bm1_15905 antibody, LOAG_18214 antibody, Hdac11 antibody
    Background
    HDAC11 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. The predominantly nuclear HDAC11, which interacts with HDAC6, is weakly expressed in most tissues, and strongly expressed in brain, heart, skeletal muscle, kidney and testis. Its activity is inhibited by trapoxin, a known histone deacetylase inhibitor.
    Molecular Weight
    39183
    Gene ID
    79885
    NCBI Accession
    NP_001129513, NP_079103
    UniProt
    Q96DB2
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