SUMO1/sentrin Specific Peptidase 5 (SENP5) (AA 524-555), (C-Term) antibody

Details for Product No. ABIN388050
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Antigen
Epitope
AA 524-555, C-Term
(35), (15), (15), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Reactivity
Human
(92), (31), (20), (1), (1)
Host
Rabbit
(89), (3)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(7), (7), (7), (6), (6), (6), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(66), (51), (45), (10), (9), (7), (1), (1)
Pubmed 2 references available
Quantity 400 μL
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Immunogen This SENP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 524-555 AA from the C-terminal region of human SENP5.
Clone RB0660
Isotype Ig
Specificity This SENP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223~252 amino acids from the C-terminal region of human SENP5.
Predicted Reactivity Mouse (Murine),Monkey
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name SENP5 (SENP5 Antibody Abstract)
Background SENP5 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its conjugatable mature form and deconjugation of SUMO2 and SUMO3 from targeted substrates. This protein has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates. SENP5 is required for cell division.
Synonyms: Sentrin-specific protease 5, Sentrin/SUMO-specific protease SENP5, FKSG45
Molecular Weight 86733 DA
Gene ID 205564
UniProt Q96HI0
Research Area Protein Modifications, Cell Cycle, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-SUMO1/sentrin Specific Peptidase 5 (SENP5) (AA 524-555), (C-Term) antibody Western blot analysis of SENP5 polyclonal antibody (ABIN388050) in Saos-2 cell lysate...
anti-SUMO1/sentrin Specific Peptidase 5 (SENP5) (AA 524-555), (C-Term) antibody (2) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
anti-SUMO1/sentrin Specific Peptidase 5 (SENP5) (AA 524-555), (C-Term) antibody (3) Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with SENP5 A...
Product cited in: Cheng, Guo, Gong et al.: "Sentrin/small ubiquitin-like modifier-specific protease 5 protects oral cancer cells from oxidative stress-induced apoptosis." in: Molecular medicine reports, Vol. 12, Issue 2, pp. 2009-14, 2015 (PubMed).

Background publications Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Validation Images
Catalog No. ABIN388050
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