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BOK antibody (AA 60-90)

BOK Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN388103
  • Target See all BOK Antibodies
    BOK (BCL2-Related Ovarian Killer (BOK))
    Binding Specificity
    • 14
    • 12
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 60-90
    Reactivity
    • 44
    • 12
    • 6
    • 1
    • 1
    • 1
    Human
    Host
    • 42
    • 2
    Rabbit
    Clonality
    • 44
    Polyclonal
    Conjugate
    • 19
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BOK antibody is un-conjugated
    Application
    • 28
    • 27
    • 13
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    M, Rat
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product BOK Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Kurata, Yanagisawa, Ohira, Kitagawa, Nakagawara, Kamijo: "Stress via p53 pathway causes apoptosis by mitochondrial Noxa upregulation in doxorubicin-treated neuroblastoma cells." in: Oncogene, Vol. 27, Issue 6, pp. 741-54, (2008) (PubMed).

    Gao, Fu, Dürrenberger, De Geyter, Zhang: "Membrane translocation and oligomerization of hBok are triggered in response to apoptotic stimuli and Bnip3." in: Cellular and molecular life sciences : CMLS, Vol. 62, Issue 9, pp. 1015-24, (2005) (PubMed).

    Yakovlev, Di Giovanni, Wang, Liu, Stoica, Faden: "BOK and NOXA are essential mediators of p53-dependent apoptosis." in: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28367-74, (2004) (PubMed).

  • Target
    BOK (BCL2-Related Ovarian Killer (BOK))
    Alternative Name
    Bok (BOK Products)
    Synonyms
    BOK antibody, bok antibody, zgc:100979 antibody, zgc:64041 antibody, BCL2L9 antibody, BOKL antibody, Bok-BH3 antibody, AI847676 antibody, AU021146 antibody, matador antibody, mtd antibody, BOK, BCL2 family apoptosis regulator antibody, BCL2-related ovarian killer a antibody, BCL2-related ovarian killer b antibody, BCL2-related ovarian killer antibody, BOK antibody, boka antibody, bokb antibody, Bok antibody
    Background
    Bok belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains all four BCL-2 like domains (BH1, 2, 3 and 4) and is a pro-apoptotic BCL-2 protein identified in the ovary.
    Gene ID
    666
    NCBI Accession
    NP_115904
    UniProt
    Q9UL32
    Pathways
    Positive Regulation of Endopeptidase Activity
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