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HTRA1 antibody (N-Term)

HTRA1 Reactivity: Human, Mouse WB, IF, IHC (p) Host: Rabbit Polyclonal RB02326 unconjugated
Catalog No. ABIN388127
  • Target See all HTRA1 Antibodies
    HTRA1 (HtrA Serine Peptidase 1 (HTRA1))
    Binding Specificity
    • 14
    • 13
    • 8
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 116-147, N-Term
    Reactivity
    • 58
    • 14
    • 11
    • 2
    • 2
    • 2
    • 1
    Human, Mouse
    Host
    • 60
    • 1
    Rabbit
    Clonality
    • 61
    Polyclonal
    Conjugate
    • 23
    • 8
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This HTRA1 antibody is un-conjugated
    Application
    • 44
    • 35
    • 26
    • 12
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This HtrA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-147 amino acids from the N-terminal region of human HtrA1.
    Clone
    RB02326
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. IF: 1:10~50. WB: 1:2000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze-thaw cycles.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
    Expiry Date
    6 months
  • Chamberland, Wang, Jones, Collins-Racie, LaVallie, Huang, Liu, Morris, Flannery, Yang: "Identification of a novel HtrA1-susceptible cleavage site in human aggrecan: evidence for the involvement of HtrA1 in aggrecan proteolysis in vivo." in: The Journal of biological chemistry, Vol. 284, Issue 40, pp. 27352-9, (2009) (PubMed).

  • Target
    HTRA1 (HtrA Serine Peptidase 1 (HTRA1))
    Alternative Name
    HtrA1 (HTRA1 Products)
    Synonyms
    htra1 antibody, zgc:92029 antibody, zgc:172061 antibody, l56 antibody, htra antibody, Xhtra1 antibody, prss11 antibody, MGC145723 antibody, ARMD7 antibody, CARASIL antibody, HtrA antibody, L56 antibody, ORF480 antibody, PRSS11 antibody, AI429470 antibody, HTRA antibody, Prss11 antibody, RSPP11 antibody, HTRA1 antibody, HtrA serine peptidase 1a antibody, HtrA serine peptidase 1 antibody, HtrA serine peptidase 1b antibody, Serine protease HTRA1 antibody, HtrA serine peptidase 1 S homeolog antibody, htra1a antibody, HTRA1 antibody, htra1b antibody, htra1 antibody, Htra1 antibody, htra1.S antibody
    Background
    HtrA1 a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth.
    Molecular Weight
    51287
    Gene ID
    5654
    NCBI Accession
    NP_002766
    UniProt
    Q92743
    Pathways
    Growth Factor Binding
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