APOBEC1 antibody (N-Term)

Catalog No. ABIN388144

Product Details anti-APOBEC1 Antibody

Target: APOBEC1 (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide 1 (APOBEC1))

Binding Specificity: AA 7-36, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOBEC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Apobec1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human Apobec1.

Clone: RB1746

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for APOBEC1

Target: APOBEC1 (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide 1 (APOBEC1))

Alternative Name: Apobec1 (APOBEC1 Products)

Synonyms: APOBEC-1 antibody, BEDP antibody, CDAR1 antibody, HEPR antibody, Cdar1 antibody, REPR antibody, APOBEC1 antibody, apolipoprotein B mRNA editing enzyme catalytic subunit 1 antibody, apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 antibody, APOBEC1 antibody, Apobec1 antibody

Background: APOBEC1 is involved in the production of apolipoprotein B (apoB)-48 from apoB-100. The gene spans 18 kb and contains five exons, all of which are translated. Alternative splicing produces a variant transcript that lacks exon 2 and encodes a novel 36-amino acid peptide. The exon 2-skipped transcript accounts for approximately 50 % of APOBEC1 mRNA in the adult small intestine and up to 90 % of APOBEC1 mRNA in the developing gut. Exon 2-skipping may thus be a quantitatively important mechanism for regulating the expression of this gene in the gastrointestinal tract.

Molecular Weight: 28192

Gene ID: 339

NCBI Accession: NP_001635

UniProt: P41238