APOBEC3B (PHO3) (C-Term), (AA 299-330) antibody

Details for Product No. ABIN388145
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Antigen
Epitope
C-Term, AA 299-330
Reactivity
Human, Mouse (Murine)
Host
Rabbit
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB)
Pubmed 2 references available
Quantity 400 μL
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Catalog No. ABIN388145
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Immunogen This APOBEC3B (PHO3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 299-330 AA from the C-terminal region of human APOBEC3B (PHO3).
Clone RB1748
Isotype Ig
Specificity This PHO3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307~337 amino acids from the C-terminal region of human PHO3.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Background PHO3 is a member of the cytidine deaminase gene family. The PHO3 gene is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control.
Molecular Weight 28173 DA
Gene ID 9582
UniProt Q9UH17
Research Area Cell Cycle, Signaling, Chromatin, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-APOBEC3B (PHO3) (C-Term), (AA 299-330) antibody Western blot analysis of hPHO3-D314 (ABIN388145) in mouse testis tissue lysates (35 µg/lane). PHO3 (arrow) was detected using the purified polyclonal antibody.
Background publications Jarmuz, Chester, Bayliss et al.: "An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22." in: Genomics, Vol. 79, Issue 3, pp. 285-96, 2002 (PubMed).

Wedekind, Dance, Sowden et al.: "Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business." in: Trends in genetics : TIG, Vol. 19, Issue 4, pp. 207-16, 2003 (PubMed).

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