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Details for Product No. ABIN388192

LIM Homeobox Transcription Factor 1, alpha (LMX1A) (AA 130-159), (Center) antibody

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Antigen
Synonyms LMX1, LMX1.1, Lmx1.1, dr, dreher, sst, si:ch211-260g14.3
Epitope
»Alternatives AA 130-159, Center
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN388192
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This Lmx1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-159 AA from the Central region of human Lmx1a.
Clone RB09408
Isotype Ig
Specificity This Lmx1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of mouse LMX1a.
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.
Alternative Name Lmx1a
Background Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS, MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin.
Synonyms: LIM homeobox transcription factor 1 alpha,LIM/homeobox protein LMX1A,LIM/homeobox protein 1.1,LMX-1.1, Lmx1a
Molecular Weight 42857 DA
Gene ID 110648
UniProt Q9JKU8
Research Area Stem Cells, Transcription Factors, Signaling
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Mangale, Hirokawa, Satyaki et al.: "Lhx2 selector activity specifies cortical identity and suppresses hippocampal organizer fate." in: Science (New York, N.Y.), Vol. 319, Issue 5861, pp. 304-9, 2008 (PubMed).

Alternatives for antigen "LIM Homeobox Transcription Factor 1, alpha (LMX1A)", type "Antibodies"
Hosts (34)
Reactivities (31), (27), (21), (14), (14), (13), (13), (1), (1)
Applications (25), (12), (10), (5), (5), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (9), (4), (3), (2), (1), (1)
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