Retina and Anterior Neural Fold Homeobox (RAX) (N-Term), (AA 15-46) antibody

Details for Product No. ABIN388195
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Antigen
Epitope
N-Term, AA 15-46
(13), (5), (4), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(30), (5), (5), (3), (1), (1)
Host
Rabbit
(21), (10)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(31), (18), (11), (3), (3)
Pubmed 2 references available
Quantity 400 µL
Options
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Catalog No. ABIN388195
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Immunogen This Rax antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-46 AA from the N-terminal region of human Rax.
Clone RB10426
Isotype Ig
Specificity This Rax antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23~53 amino acids from the N-terminal region of human RAX.
Predicted Reactivity Chicken
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name Rax
Background Rax plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. It binds to the photoreceptor conserved element-I (PCE-1/Ret 1) in the photoreceptor cell-specific arrestin promoter.
Synonyms: Retinal homeobox protein Rx, Retina and anterior neural fold homeobox protein, RAX
Molecular Weight 36805 DA
Gene ID 30062
UniProt Q9Y2V3
Research Area Stem Cells, Cell Cycle, Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Retina and Anterior Neural Fold Homeobox (RAX) (N-Term), (AA 15-46) antibody Western blot analysis of anti-Rax Pab (ABIN388195) in mouse brain tissue lysates (35 µg/lane). Rax(arrow) was detected using the purified polyclonal antibody.
anti-Retina and Anterior Neural Fold Homeobox (RAX) (N-Term), (AA 15-46) antibody (2) Formalin-fixed and paraffin-embedded human brain tissue reacted with Rax Antibody (N-term) (ABIN388195), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Background publications Mikkola, Bruun, Holm et al.: "Superactivation of Pax6-mediated transactivation from paired domain-binding sites by dna-independent recruitment of different homeodomain proteins." in: The Journal of biological chemistry, Vol. 276, Issue 6, pp. 4109-18, 2001 (PubMed).

Voronina, Kozhemyakina, OKernick et al.: "Mutations in the human RAX homeobox gene in a patient with anophthalmia and sclerocornea." in: Human molecular genetics, Vol. 13, Issue 3, pp. 315-22, 2004 (PubMed).

Validation Images
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