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Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) (AA 302-331), (C-Term) antibody

Details for Product No. ABIN388229, Supplier: Login to see
Antigen
  • fb14c08
  • fj51c03
  • zgc:85707
  • wu:fb14c08
  • wu:fj51c03
  • Xspred1
  • Xtspred1
  • 5730461F13Rik
  • AL024345
  • AW047647
  • NFLS
  • hSpred1
  • spred-1
Epitope
AA 302-331, C-Term
18
17
14
14
5
4
2
2
1
1
1
1
Reactivity
Human
91
18
12
Host
Rabbit
75
16
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
7
7
7
7
7
7
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
84
59
39
16
12
4
1
1
Supplier
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Immunogen This SPRED1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 302-331 AA from the C-terminal region of human SPRED1.
Clone RB11926
Isotype Ig
Specificity This SPRED1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309~339 amino acids from the C-terminal region of human SPRED1.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name SPRED1 (SPRED1 Antibody Abstract)
Background SPRED1 is a tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase.
Synonyms: Sprouty-related, EVH1 domain-containing protein 1, Spred-1, SPRED1,
Molecular Weight 50477 Da
Gene ID 161742
UniProt Q7Z699
Research Area Stem Cells, Cell Cycle, Cell Structure
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) (AA 302-331), (C-Term) antibody (ABIN388229) Western blot analysis of SPRED1 Antibody (C-term) polyclonal antibody(ABIN388229)(arr...
Immunohistochemistry (IHC) image for anti-Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) (AA 302-331), (C-Term) antibody (ABIN388229) Formalin-fixed and paraffin-embedded human brain tissue reacted with SPRED1 antibody ...
Background publications Brems, Chmara, Sahbatou et al.: "Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1-like phenotype." in: Nature genetics, Vol. 39, Issue 9, pp. 1120-6, 2007 (PubMed).

Yoshida, Hisamoto, Akiba et al.: "Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors." in: Oncogene, Vol. 25, Issue 45, pp. 6056-66, 2006 (PubMed).