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Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) (C-Term), (AA 302-331) antibody

Details for Product No. ABIN388229
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Antigen
Epitope
C-Term, AA 302-331
(8), (8), (6), (6), (5), (4), (4), (4), (1)
Reactivity
Human
(53), (15), (15)
Host
Rabbit
(45), (8)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(4), (4), (4), (4), (4), (4)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(53), (42), (24), (11), (7), (1)
Pubmed 2 references available
Quantity 400 µL
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Catalog No. ABIN388229
291.50 $
Plus shipping costs $45.00
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Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This SPRED1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 302-331 AA from the C-terminal region of human SPRED1.
Clone RB11926
Isotype Ig
Specificity This SPRED1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309~339 amino acids from the C-terminal region of human SPRED1.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name SPRED1
Background SPRED1 is a tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase.
Synonyms: Sprouty-related, EVH1 domain-containing protein 1, Spred-1, SPRED1,
Molecular Weight 50477 Da
Gene ID 161742
UniProt Q7Z699
Research Area Stem Cells, Cell Cycle, Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) (C-Term), (AA 302-331) antibody Western blot analysis of SPRED1 Antibody (C-term) polyclonal antibody(ABIN388229)(arrow). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the SPRED1 gene (Lane 2) (Origene Technologies).
anti-Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) (C-Term), (AA 302-331) antibody (2) Formalin-fixed and paraffin-embedded human brain tissue reacted with SPRED1 antibody (C-term) (ABIN388229), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Background publications Yoshida, Hisamoto, Akiba et al.: "Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors." in: Oncogene, Vol. 25, Issue 45, pp. 6056-66, 2006 (PubMed).

Brems, Chmara, Sahbatou et al.: "Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1-like phenotype." in: Nature genetics, Vol. 39, Issue 9, pp. 1120-6, 2007 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN388229
291.50 $
Plus shipping costs $45.00
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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