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Details for Product No. ABIN388229

Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) (C-Term), (AA 302-331) antibody

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Antigen
Synonyms AL024345, AW047647, 5730461F13Rik, NFLS, hSpred1, spred-1, fb14c08, fj51c03, zgc:85707, wu:fb14c08, wu:fj51c03, Xspred1, Xtspred1
Epitope
»Alternatives C-Term, AA 302-331
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN388229
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This SPRED1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 302-331 AA from the C-terminal region of human SPRED1.
Clone RB11926
Isotype Ig
Specificity This SPRED1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309~339 amino acids from the C-terminal region of human SPRED1.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name SPRED1
Background SPRED1 is a tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase.
Synonyms: Sprouty-related, EVH1 domain-containing protein 1, Spred-1, SPRED1,
Molecular Weight 50477 Da
Gene ID 161742
UniProt Q7Z699
Research Area Stem Cells, Cell Cycle, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Yoshida, Hisamoto, Akiba et al.: "Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors." in: Oncogene, Vol. 25, Issue 45, pp. 6056-66, 2006 (PubMed).

Brems, Chmara, Sahbatou et al.: "Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1-like phenotype." in: Nature genetics, Vol. 39, Issue 9, pp. 1120-6, 2007 (PubMed).

Alternatives for antigen "Sprouty-Related, EVH1 Domain Containing 1 (SPRED1)", type "Antibodies"
Hosts (30), (6)
Reactivities (36), (18), (13)
Applications (36), (17), (13), (10), (3)
Epitopes (5), (4), (4), (4), (3), (3), (2), (1)
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