RAB23, Member RAS Oncogene Family (RAB23) (C-Term) antibody

Antigen: RAB23, Member RAS Oncogene Family (RAB23)

Synonyms: HSPC137, MGC8900, DKFZp781H0695, opb, opb2, AW545388, MGC82152, hspc137, MGC107825, MGC110261, zgc:110261, Rab23-like

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN388242

Additional Information

Alternative name: RAB23

Gene ID: 51715

UniProt: Q9ULC3

Immunogen: This RAB23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208~237 amino acids from the C-terminal region of human RAB23.

Isotype: Ig

Characteristics: Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This RAB23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208~237 amino acids from the C-terminal region of human RAB23.

Molecular Weight: 26528 DA

Comments:

Background: The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It may be involved in small GTPase mediated signal transduction and intracellular protein transportation. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

Application Details

Application Notes: The suggested dilution is: ELISA1:1,000 Western blotting 1:50~100

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Stem Cells, Cell Signaling, Cell Structure

Restrictions: For Research Use only

Images

Western blot analysis of RAB23 (arrow) using rabbit polyclonal RAB23 Antibody (C-term)(ABIN388242). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the RAB23 gene (Lane 2) (Origene Technologies).

Publications

Product: Liu, Wang, Li et al.: "Rab23 is a potential biological target for treating hepatocellular carcinoma." in: World journal of gastroenterology : WJG, Vol. 13, Issue 7, pp. 1010-7, 2007 (PubMed).

Jenkins, Seelow, Jehee et al.: "RAB23 mutations in Carpenter syndrome imply an unexpected role for hedgehog signaling in cranial-suture development and obesity." in: American journal of human genetics, Vol. 80, Issue 6, pp. 1162-70, 2007 (PubMed).